DRSC/TRiP Functional Genomics Resources

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Protein Alignment dmGlut and SLC17A2

DIOPT Version :9

Sequence 1:NP_620115.2 Gene:dmGlut / 47253 FlyBaseID:FBgn0010497 Length:496 Species:Drosophila melanogaster
Sequence 2:NP_001273052.1 Gene:SLC17A2 / 10246 HGNCID:10930 Length:478 Species:Homo sapiens


Alignment Length:468 Identity:146/468 - (31%)
Similarity:239/468 - (51%) Gaps:27/468 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 QWGISL----SRYFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPD 66
            ::|::|    |.:.:|.|||.|:| ..:|::|. |.:..||.|.|...| .::.::.|.:|.|  
Human    17 RYGLALIMHFSNFTMITQRVSLSI-AIIAMVNT-TQQQGLSNASTEGPV-ADAFNNSSISIKE-- 76

  Fly    67 DIDEGTSVGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTP 131
             .|...||   ::||.|.||:|.||...|.|:|.||.|.||..||.|..||.|:|.:::.|:.||
Human    77 -FDTKASV---YQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFTP 137

  Fly   132 LAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSG 196
            ||.:.| ...:|:.|.:.|:.:|..:.....:.|.|.|..||.||..:...|...|:.:...:.|
Human   138 LAADFG-VILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVGG 201

  Fly   197 VFIDAYGWEFVFYFFGGLGVV----WFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRNEDL 257
            :...|..|.|:||.||..|.|    ||.:.    |.||..||.|...|:|::   :.::::....
Human   202 LISQALSWPFIFYIFGSTGCVCCLLWFTVI----YDDPMHHPCISVREKEHI---LSSLAQQPSS 259

  Fly   258 P--PTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWI 320
            |  ..|.||::|.||::|:......|.|...|::|.||.|::.:|..:|:.:|:.||||::....
Human   260 PGRAVPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFIAAAS 324

  Fly   321 VSVGSGFVADWMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGA 385
            .::..|.:||:::.|.:|.....||:.:.|....|:|..|...:.....|:.::|..:..|....
Human   325 CTILGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSICAVALPFVASSYVITIILLILIPGTSNL 389

  Fly   386 YYAGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFT 450
            ..:|..::.||::|.||..||.|:.|.|.|.|:|:....|.:........||.||:::..|..|.
Human   390 CDSGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLISQDFESGWRNVFFLSAAVNMFG 454

  Fly   451 AVIYCIWASGEVQ 463
            .|.|..:...|:|
Human   455 LVFYLTFGQAELQ 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dmGlutNP_620115.2 2A0114euk 25..463 CDD:129972 137/443 (31%)
MFS 77..458 CDD:119392 121/386 (31%)
SLC17A2NP_001273052.1 2A0114euk 1..477 CDD:129972 146/468 (31%)
MFS 81..461 CDD:119392 123/390 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148703
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2532
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D347586at33208
OrthoFinder 1 1.000 - - FOG0000034
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.750

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