Protein Alignment dmGlut and slc17a8

DIOPT Version :10

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_002936892.1
• Gene: slc17a8 / 100489470
• XenbaseID: XB-GENE-988965
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 162/502 - (32%)
• Similarity: 253/502 - (50%)
• Gaps: 48/502 - (9%)

  Fly    17 IPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSVGGDFEWS 81
            ||:|.|:|:|..|....::.:|..|..|| |.:|..|:...|.:...:.          ..|.|.
 Frog    72 IPKRYIIAMMSGLGFCISFGIRCNLGVAI-VEMVNNNTVYVDGKPEMQK----------AQFNWD 125

  Fly    82 EELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLA--INKGDSDWLIV 144
            .|..|||..||:.|||:|.||||.:|.|.......|..|..|::..||.|.|  ::.|   .:|.
 Frog   126 PETVGLIHGSFFWGYIITQIPGGFIANKLAANRVFGAAIFLTSILNMLIPSAARVHFG---CVIS 187

  Fly   145 TRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDAYGWEFVFY 209
            .|||.||.||.|:||...:.:.|.|..||.:|......|...|.::...|:||.:...||..|||
 Frog   188 VRVLQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLVQYIGWPSVFY 252

  Fly   210 FFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIG------TISRNEDLPPTPWKAILTN 268
            .:|..|:.|:..::......|.:||.|...||.|:...||      |..:.:    ||||...|:
 Frog   253 IYGVFGMCWYVFWLLHATESPAAHPSITFEERTYIETSIGEGSNLVTTGKFK----TPWKKFFTS 313

  Fly   269 LPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMI 333
            :|::|::.|.....|.||:::...|.|..:|..|.|...||.|::|:::|.|:....|.:||::.
 Frog   314 MPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGLLSAVPHMVMTIIVPVGGQLADFLR 378

  Fly   334 RRGVLSTTNTRKVMT--GLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYYAGMKLSPLD 396
            .|.:||||..||:|.  |.......:.:||.|:.   :.:.:....:.:|..|...:|..::.||
 Frog   379 SRKILSTTTVRKIMNCGGFGMEATLLLVVGYSHT---KAISISFLVLAVGFSGFAISGFNVNHLD 440

  Fly   397 MSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVI-YCIWASG 460
            ::|.||..||.|:||:|.::|::.|.:||.||.|.:..||:.||.:| .::.::.|| |.|:|||
 Frog   441 IAPRYASILMGISNGVGTLSGMVCPLIVGAMTKNKTREEWQNVFLIA-AIVHYSGVIFYGIFASG 504

  Fly   461 EVQPFNNAPIQPRSV----------DFEAQERKVGGEK-TSGLEQSS 496
            |.|.:    ..|.|:          |..|:|.::..|. ||..::||
 Frog   505 EKQEW----ADPESLSEDKCGIIDNDELAEETELNNESFTSSNKKSS 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	MFS_SLC17	24..458	CDD:340876	143/444 (32%)
slc17a8	XP_002936892.1	MFS_SLC17A6_7_8_VGluT	79..502	CDD:340940	143/444 (32%)