Protein Alignment SrpRalpha and F38A1.8

DIOPT Version :10

• Sequence 1: NP_524887.2
• Gene: SrpRalpha / 47251
• FlyBaseID: FBgn0010391
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_741303.2
• Gene: F38A1.8 / 185438
• WormBaseID: WBGene00009521
• Length: 625
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 322/657 - (49%)
• Similarity: 432/657 - (65%)
• Gaps: 77/657 - (11%)

  Fly     1 MLDFVVIFTKGGVVLWHSNASGNSFASCINS-LIRGVILEERNTEAKYYEEDHLAVQFKLDNELD 64
            |::...|||||||.||:......:|...||: ||:|.::|||....: .:..:..::|:||||.:
 Worm     1 MIELFSIFTKGGVCLWNYQEGDYNFTEAINNELIKGTLMEERGNSGQ-KKVGNYTMKFQLDNEYN 64

  Fly    65 LVYAAIFQKVIKLNY--------LDGFLADMQAAFKEK----------YGDIRLGDDYDFDREYR 111
            :::..|:|.::.|||        :|.|..:.....:|:          ||        :||..:.
 Worm    65 VIFLVIYQTIVNLNYAEKLLNLVVDSFRGEFSENLREETALTTPPSNIYG--------NFDETFH 121

  Fly   112 RVLS-AAEEASAKQ--VKAPKTMRSYNESQKSKKTVASMI--QDDKKPVEKRV-NIQEAP--PPS 168
            .||| ||:.|.|.:  ||.|||   :.||.||:||:.|:|  :..:|..||.. |.::.|  |..
 Worm   122 EVLSEAAKSARATENTVKKPKT---FQESAKSQKTIDSLIVSRPGQKNAEKSAKNAEKTPKKPVE 183

  Fly   169 KSQPSS-------PPTGSPMDKIIMEKRRKLREKLT-PTKKTSPSDSKSSKPEKAGKKPRVWDLG 225
            .::.||       .|.||| |:.::.:|.::.:|:: .|||..|.:..|.||:  ||:.|||.|.
 Worm   184 SAEESSATDYNSASPPGSP-DEEVLRRRDQMFKKMSGNTKKKGPEEPTSPKPK--GKQARVWALS 245

  Fly   226 GNSKDAALLDRS------RDSPDDVQYQNINS--ELVGTMQGVIRDLDVESEDEADNEDASSEGE 282
            |...|...||||      .::.|:.:.:.:.|  |.:||::|     |::|..|:|:||   |.:
 Worm   246 GKPADVKNLDRSDPKENDENAADEEKNRFVESMKEQIGTLKG-----DLKSLQESDDED---EDD 302

  Fly   283 AEEQVQSKKGKRGGLLSYFKGIVGAKTMSLADLQPALEKMRDHLISKNVASEIAAKLCDSVAASL 347
            .::||..:.   ||..|..||:||.|.:|..||.|.:||||::||.||||||.|.|:|.||.:.|
 Worm   303 NDQQVVKQS---GGWFSMIKGLVGEKKLSAEDLNPLIEKMRENLILKNVASEPAEKICQSVVSKL 364

  Fly   348 DGKQMGTFDSIASQVKEALTESLVRILSPKRRIDIIRDALESKRNGRPYTIIFCGVNGVGKSTNL 412
            :||.:..|..:|.:||.|:.||||::|:||.|:||:||.:|:||:||||.|:|||||||||||||
 Worm   365 EGKVVNNFSRVAQEVKTAVRESLVQLLTPKHRVDILRDVIEAKRDGRPYVIVFCGVNGVGKSTNL 429

  Fly   413 AKICFWLIENDFNVLIAACDTFRAGAVEQLRTHTRHLNALHPAAKHDGRNMVQLYEKGYGKDAAG 477
            |||.|||.||...|||||.||||||||||||||.|:||.||       :|.|.|:|:|||||.||
 Worm   430 AKITFWLTENKHRVLIAAGDTFRAGAVEQLRTHARYLNDLH-------KNSVLLHEQGYGKDPAG 487

  Fly   478 IAMEAIKFAHDTRVDVVLVDTAGRMQDNEPLMRSLSKLIKVNNPDLVLFVGEALVGNEAVDQLVK 542
            :|..|||.|.:...|||||||||||||||||||.|:|||:||.||||||||||||||||||||||
 Worm   488 LAAAAIKKAAEQDFDVVLVDTAGRMQDNEPLMRELAKLIRVNEPDLVLFVGEALVGNEAVDQLVK 552

  Fly   543 FNQSLADYSS-NENPHIIDGIVLTKFDTIDDKVGAAISMTYITGQPIVFVGTGQTYADLKAINVN 606
            ||::||:::| .:.|.:|||||||||||||||||||:||||||||||||||.||||:||:.:||.
 Worm   553 FNEALANHASPGQKPRLIDGIVLTKFDTIDDKVGAAVSMTYITGQPIVFVGCGQTYSDLRNLNVG 617

  Fly   607 AVVNSLM 613
            |||:||:
 Worm   618 AVVHSLL 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SrpRalpha	NP_524887.2	SRP-alpha_N	28..267	CDD:461165	86/281 (31%)
		FlhF	<258..500	CDD:274609	135/241 (56%)
		SRalpha_C	396..612	CDD:349785	160/216 (74%)
F38A1.8	NP_741303.2	SRP-alpha_N	29..292	CDD:461165	86/282 (30%)
		SRP54_N	318..391	CDD:214941	38/72 (53%)
		SRalpha_C	413..623	CDD:349785	160/216 (74%)