DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment woc and ZMYM1

DIOPT Version :9

Sequence 1:	NP_001097946.1	Gene:	woc / 47249	FlyBaseID:	FBgn0010328	Length:	1703	Species:	Drosophila melanogaster
Sequence 2:	XP_024305590.1	Gene:	ZMYM1 / 79830	HGNCID:	26253	Length:	1193	Species:	Homo sapiens

Alignment Length:	320	Identity:	77/320 - (24%)
Similarity:	119/320 - (37%)	Gaps:	57/320 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   709 QFCCAGCLNTFKKG--------------------------------LKTCSCCQKDISGGQEGFL 741
            |..||||....:||                                .:|||.|.|||...::...
Human   137 QVSCAGCKKILQKGQTAYQRKGSAQLFCSIPCITEYISSASSPVPSKRTCSNCSKDILNPKDVIS 201

  Fly   742 APVGDKDQFKDFCSQSCLRRYESMCNPRRKLRTD----VCGVCNNQKPVRVEMLLEDREHYFCSN 802
            ..:.|....|.|||.|||..||....|...:.|:    .|.:|.....::.|:..::.:|..|||
Human   202 VQLEDTTSCKTFCSLSCLSSYEEKRKPFVTICTNSILTKCSMCQKTAIIQYEVKYQNVKHNLCSN 266

  Fly   803 PCFSAFKFVSNVNADPCAMCSKYFERRSAESYTIYNEQQSPKVFCSRVCINVYIIVNRHIVSCQW 867
            .|.|.|...:|...:.|..|..|....|:.|:.:..|.|| ..|.|...|..|.......:....
Human   267 ACLSKFHSANNFIMNCCENCGTYCYTSSSLSHILQMEGQS-HYFNSSKSITAYKQKPAKPLISVP 330

  Fly   868 CKVKKYNFDMIYQIGGPHDQETLTCSINCLTMHG----VSCNISARAVTKCDNCSNFNTPQYHLT 928
            ||..|.:.:|| :......:..|.|||||.:.:.    .|.::|..:|.. |..:...:|:...|
Human   331 CKPLKPSDEMI-ETTSDLGKTELFCSINCFSAYSKAKMESSSVSVVSVVH-DTSTELLSPKKDTT 393

  Fly   929 MSDASMRNFCTYQCVMQFQNQ----------FARAPLTLD----SDLPPSSAGSSKSQQQ 974
            ...:::.:.......:...|.          .|.|.:.:|    |...||:|.:|.|.:|
Human   394 PVISNIVSLADTDVALPIMNTDVLQDTVSSVTATADVIVDLSKSSPSEPSNAVASSSTEQ 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
woc	NP_001097946.1	TRASH	684..721	CDD:214799	5/11 (45%)
		zf-FCS	724..762	CDD:283998	15/37 (41%)
		DUF3504	1531..1690	CDD:288835
ZMYM1	XP_024305590.1	zf-FCS	182..222	CDD:310814	15/39 (38%)
		ZnF_TTF	503..582	CDD:214739
		DUF4371	544..778	CDD:316782
		Dimer_Tnp_hAT	1080..1169	CDD:310361
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.110