Protein Alignment woc and Zmym2

DIOPT Version :10

• Sequence 1: NP_001097946.1
• Gene: woc / 47249
• FlyBaseID: FBgn0010328
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_011243521.1
• Gene: Zmym2 / 76007
• MGIID: 1923257
• Length: 1402
• Species: Mus musculus
• Alignment Length: 1550
• Identity: 390/1550 - (25%)
• Similarity: 606/1550 - (39%)
• Gaps: 416/1550 - (26%)

  Fly   348 EDDSAAAVDATDVSPTTPTDAQAGAKSAATGIAEADGV--AAAANEEEAGGDVPDPDEPTAEESS 410
            |||.    |...:.|..|      ..|:|..:|:...:  .::.|||..|.|      |....||
Mouse    55 EDDD----DVVFIEPVQP------PPSSAPLVADQRPITFTSSKNEELQGND------PKILPSS 103

  Fly   411 SAGAGEPGSTPKIIISWIVGSVQKCKQCGDEK-NCGFRYRSPEESEEMDKEKEND---------K 465
            ...|.:.||..:.|:  |..........|.|| :..|..|.|.|:    |.:.||         :
Mouse   104 KELAPQKGSVSETIV--IDDEEDMETNQGQEKSSSNFIERRPSET----KNRTNDVDFSSSTFSR 162

  Fly   466 AEENA---------EEGEEEEARQKPAAPSGFEYICDTACVDALLEDQPGKYFVRRKKFLVEEVV 521
            ::.||         |...|.:........:|...:.     |..||...|    |....::..|.
Mouse   163 SKVNAGVSNSGITTEPDSEIQIANVTTLETGVSSVS-----DGQLESTDG----RDMNLMITHVT 218

  Fly   522 REEGAAEAEASADGEGGDAE-------EEATPANTQDCLQCKDKTRCKYFIKQDQDCFYICNDDC 579
                :....:..||..|...       :..||:.|.   |.|                  .....
Mouse   219 ----SLHNTSLGDGSNGLQSSNFGVNIQTYTPSLTS---QTK------------------AGVGP 258

  Fly   580 FNLLNAEEPDKFKLKRHSIRVRNIGATTLQPPQNSPTKRTDGSVVARTVEEAETARLDRIESFRR 644
            ||      |.:.          |:.....|..:::|....|..:       :::|...|.:  ::
Mouse   259 FN------PGRM----------NVAGDVFQNGESAPHHNPDSWI-------SQSASFPRNQ--KQ 298

  Fly   645 RCADCEADINTDEKQLMWETMDFCNEVCLGSYQRT--IGSTCETCKQEVSSIALGKYCVRFGFDV 707
            :..|..:.:.:..||:...:          :.|.|  :..||..||:.:..   |:...:.....
Mouse   299 QGVDSLSPVASLPKQIFQPS----------NQQPTKPVKVTCANCKKPLQK---GQTAYQRKGSA 350

  Fly   708 RQFCCAGCLNTFK---KGLKTCSCCQKDISGGQEGFLAPVGDKDQFKDFCSQSCLRRYESMCNPR 769
            ..||...||::|.   ...|.|..|:|||:..:...:|.|...:.|::|||.|||..||...:|.
Mouse   351 HLFCSTTCLSSFSHKPAPKKLCVMCKKDITTMKGTIVAQVDSSESFQEFCSTSCLSLYEDKQSPA 415

  Fly   770 R-KLRTDVCGVCNNQKPVRVEMLLEDREHYFCSNPCFSAFKFVSNVNADPCAMCSKYFERRSAES 833
            : .|....|.:|.....:|.|:..::..|..||:.||:.::..:.:..:.|..|.:|...:.|.:
Mouse   416 KGALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRMANGLIMNCCEQCGEYLPSKGAGN 480

  Fly   834 YTIYNEQQSPKVFCSRVCINVYIIVNRH------------------------IVSCQWCKVKKYN 874
            ..:..:.|. |.||.:.|:..|..|..|                        :.:|..|:.:...
Mouse   481 NVLVVDGQQ-KRFCCQSCVTEYKQVGSHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRF 544

  Fly   875 FDMIYQIGGPHDQETLTCSINCLTMHGVSCNISARAVTKCDNCSNFNTPQYHLTMSDASMRNFCT 939
            |||. |..||:......||..|:..|......|......|..|...:.|||..||.|..:.|||.
Mouse   545 FDMT-QCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCN 608

  Fly   940 YQCVMQFQNQFARAPLTLDSDLPPSSAGSSKSQQQSNRGNKNAAPFPTGLPKRVKLKLSHTGKGG 1004
            ..||.:||                     :.|.|.|..|...|       |..::||.::. |..
Mouse   609 SSCVAKFQ---------------------ALSMQSSPNGQFVA-------PSDIQLKCNYC-KNS 644

  Fly  1005 VGGKK--------------------------------------------SGSGTMLPVIST-VQS 1024
            ...|.                                            :.||...|..|. .:.
Mouse   645 FCSKPEILEWENKVHQFCSKTCSDDYKKLHCIVTYCEYCQEEKTLHETVNFSGVKRPFCSEGCKL 709

  Fly  1025 LASGETEARIGNLTVR-------RKRGRPRE--------------------------------SG 1050
            |...:...|:|...|.       .|:|..:|                                .|
Mouse   710 LYKQDFARRLGLRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQEWYYKAARCDCCKSQG 774

  Fly  1051 TSSPPLSMPGVHPPAQRGRPRKHAVDY--------SARSPSPTMSGGSSHMGIPVRRNTTTTMDF 1107
            |....:...|         ..||..|.        ....|:.|...|..::.......|:.|...
Mouse   775 TLKERVQWRG---------EMKHFCDQHCLLRFYCQQNEPNMTTQKGPENLHYDQGCQTSRTKMT 830

  Fly  1108 GPATVTETKIITVPPYP---KAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEKDYSNK-VLIPV 1168
            |.|.         ||.|   |.::|..|.|||||:|:...|.|.::..:.||::::..: |.:|:
Mouse   831 GSAP---------PPSPTPNKEMKNKAILCKPLTMTKATYCKPHMQTKSCQTDENWKTEYVPVPI 886

  Fly  1169 PVPIFVPQPMYMYSAPFPVPVPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLM 1233
            |||::||.||:|||...|||..:|:|:|||:|:|...::::.|...::.::.|:..|||::|||.
Mouse   887 PVPVYVPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPATVEDLKSKVSSDPLDSELLT 951

  Fly  1234 MAEMVAEEKHESDSDSDNE--------------------IKPDPGLVALQ--YQNSLESVAQQQQ 1276
            |.:|:.||:.::::.:.|.                    ..|:.|::...  ..:.|...:....
Mouse   952 MTDMMTEEEGKAEASNINSGDFVCVLGSKLLASRQGLPASSPEVGVIIETDIIGSDLTKNSDPDI 1016

  Fly  1277 QQQVVDVSGAGHNPYGDDM-LQIALKMATGDYDNHHQTSTVDLETSMTANTISSQSPMGHDGMGQ 1340
            |..:.||      ||..|: ::|....|..:         :|:|.......:
Mouse  1017 QSNMPDV------PYEPDLDIEIDFPRAAEE---------LDMENEFLLPPV------------- 1053

  Fly  1341 MGVHHLDQQHHMLDATQRTARGRKRGVGVVMDPPNRNSRSPVKRQR-GGEMDHSALQQQSQQAQQ 1404
            .|..:.:|                        |..|:.:...||:. .|...|          ..
Mouse  1054 FGEEYEEQ------------------------PRPRSKKKGTKRKAVSGYQSH----------DD 1084

  Fly  1405 PQEKPDAQMFLKYTFGVNAWKQWVMTKNAD------IEKSSMRRRPFKTELLQMTADELNYSLCL 1463
            ..:..:.....|||:||||||.||.|:..|      .|..|.:....|.:||..|..||||.|..
Mouse  1085 SSDNSECSFPFKYTYGVNAWKHWVKTRQLDEDLLVLDELKSSKSVKLKEDLLSHTTAELNYGLAH 1149

  Fly  1464 FVKEVRKPNGTEYAPDTIYYLVLGIQQYLYVNGRIDNIFYDPYYERFTECLDEVARKF--SVLYN 1526
            ||.|:|:|||..||||:||||.||||:||..:.|.||||.||.|:.|.:.|:::.|.:  |:|.:
Mouse  1150 FVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQMFEQELNKILRSWQPSILPD 1214

  Fly  1527 DSQYIVTRVEEEHLWECKQLGAHSPHVLLSTLMFFNTKHFNLTTVEEHMQLSFSHIMKHWKRSS- 1590
            .|  |.:||||::||..||||:|||..||:||.:||||:|.|.|||:|::|||..:.:|||::.
Mouse  1215 GS--IFSRVEEDYLWRIKQLGSHSPVALLNTLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPL 1277

  Fly  1591 ----------QNSKVPGSRNVLLRFYPPQAGLDANPRK----KKVYEQQENEENPLRCPVRLYEF 1641
                      |.|.:.|:.|        :..:....||    :.|:||.||..||.||||:::|.
Mouse  1278 TMENKACLRYQVSSLCGTDN--------EDKIATGKRKHEDDEPVFEQVENTANPSRCPVKMFEC 1334

  Fly  1642 YLSKCPESVKTRNDVFYLQPERSCVPDSPVWYSTQALGQDALQRMLHRVKMVKEI 1696
            ||||.|:::..|.||||||||.|...||||||::.:|.::.|:.||.||.:||:|
Mouse  1335 YLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRNTLENMLVRVLLVKDI 1389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
woc	NP_001097946.1	MDN1	<7..>419	CDD:444083	18/72 (25%)
		TRASH	684..721	CDD:214799	9/39 (23%)
		zf-FCS	724..762	CDD:428958	15/37 (41%)
		DUF3504	1531..1692	CDD:463430	79/175 (45%)
Zmym2	XP_011243521.1	zf-FCS	326..362	CDD:428958	9/38 (24%)
		zf-FCS	367..408	CDD:428958	15/40 (38%)
		zf-FCS	419..455	CDD:428958	10/35 (29%)
		zf-FCS	461..501	CDD:428958	9/40 (23%)
		zf-FCS	530..569	CDD:428958	11/39 (28%)
		zf-FCS	633..670	CDD:428958	4/37 (11%)
		zf-FCS	721..757	CDD:428958	4/35 (11%)
		zf-FCS	763..798	CDD:428958	6/43 (14%)
		DUF3504	1217..1385	CDD:463430	79/175 (45%)