Protein Alignment woc and zmym4.2

DIOPT Version :9

• Sequence 1: NP_001097946.1
• Gene: woc / 47249
• FlyBaseID: FBgn0010328
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_005159756.1
• Gene: zmym4.2 / 553317
• ZFINID: ZDB-GENE-060503-672
• Length: 1565
• Species: Danio rerio
• Alignment Length: 1733
• Identity: 442/1733 - (25%)
• Similarity: 676/1733 - (39%)
• Gaps: 485/1733 - (27%)

  Fly   203 VDMQSVGADSHQAEDAEPPEG---RDEVDTSLEEQENGQDPDEREKDAAADEDDPDAEGDAESEQ 264
            :|...:.::....||.:|.||   |....:::.....|.:|:|...:..|:|   :.|.|.||:.
Zfish    61 IDGSRLCSEHFTPEDYKPDEGQIRRLLKSSAVPVPVQGFEPNEVCIELDANE---ETEIDPESQS 122

  Fly   265 VDENAEETGEAEHGDDTVENVLEPEESDVCLIPDDQETEVTEAEKELARENAEKAAEEEEAEERQ 329
            :|::.:...|..:.||                 ||      :.:..:.|:...::...|..:.|.
Zfish   123 IDDSFDFEDEEAYFDD-----------------DD------DIQSTVGRQKNPRSCPGERLQSRL 164

  Fly   330 AKTPDNDRKSPADAAADPEDDSAAAVDAT--DVSPT------TPTDAQAGAKSAATGIAEADGVA 386
            ..|..|....|.         :..:|..|  .:|||      .|:......:.........|.||
Zfish   165 ILTVTNPSTEPT---------TPPSVFGTYYALSPTWYYQMDDPSKIGLHMEEPFNENVNMDFVA 220

  Fly   387 AAANEEEAGGDV----------------PDPDEPTAEESSSAGAGEPGSTPKIIISWIVGSVQKC 435
                .:||||.:                |:...|.:::..|..:. ||
Zfish   221 ----NKEAGGFLNHELSKGHSHVCRRSRPEKRNPLSQDRGSKRSA-PG----------------- 263

  Fly   436 KQCGDEKNCGFRYRSPEESEEMDKEKENDKAEENAEEGEE------EEARQKPAAPSGFEYICDT 494
                          |||::.:.|.|.::...||||:..||      |:...:........|   :
Zfish   264 --------------SPEDATDSDNEDKDINTEENAQCSEELVITKVEDLSNETEFDQNENY---S 311

  Fly   495 ACVDALLEDQPGKYFVRRKKFLVEEVVREEGAAEAEASADGEGGDAEEEATPANTQDCLQCKDKT 559
            ..:|.   |:|......|.|.|...........:.:|:.....|....:..|      ::.||:.
Zfish   312 GKMDM---DEPEDSEALRAKGLKSRPAHSSAVTQTQAADKRFAGFDPSDVLP------VKIKDEP 367

  Fly   560 RCKYFIKQDQDCFYICNDDCFNLLNAEEPDKFKLKRHSIRVRNIGATTLQPPQNSPTKRTDGSVV 624
            ..:.:.|..|.......||       |:.|:.:|..:.           |.|
Zfish   368 MDEEWKKAPQSPLRSIKDD-------EDFDQQRLGSYH-----------QVP------------- 401

  Fly   625 ARTVEEAET-ARLDRIESFRRRCADCEADINTDEKQLMWETMDFCNEVCL---GSYQRTIGSTCE 685
              .|..|.| |:.:.|::|:|....|.|                ||:|.|   .::||: ||
Zfish   402 --GVNNASTGAQTESIQNFKRLGVLCTA----------------CNKVLLKGQTAFQRS-GS--- 444

  Fly   686 TCKQEVSSIALGKYCVRFGFDVRQFCCAGCLNTFKKGLKTCSCCQKDISGGQEGFLAPVGDKDQF 750
                                 .:.:|...||.:.|.  |.|..|.|:|.......:|||......
Zfish   445 ---------------------AKIYCSLECLRSTKN--KACHHCLKEIHEDSSIIVAPVDMSGAG 486

  Fly   751 KDFCSQSCLRRYESMCNPRRKLRTDVCGVCNNQKPVRV-EMLLEDREHYFCSNPCFSAFKFVSNV 814
            |:||||.|           |...|..|.||.......| |:.........||:.||:.|:..:.:
Zfish   487 KEFCSQKC-----------RNALTFKCSVCQKAGIRHVHEVNFRGSIQKLCSDGCFNQFRSSNKL 540

  Fly   815 NADPCAMCSKYFERRSAESYTIYNEQQSPKVFCSRVCINVYIIVNRHIVSCQWCKVKKYNFDMIY 879
            |.:.|..|..:.....|:..::..|.:..| |||:.|:..|...:..:|:|:.|...:...|
Zfish   541 NMNSCVNCGGFCYGTDAQCPSLRMEDRVMK-FCSQTCLTAYKKRSLKLVTCKTCHALRPAED--- 601

  Fly   880 QIGGPHDQ--ETLTCSINCLT-MHGVSCNISARAVTKCDNCSNFNTPQYHLTMSDASMRNFCTYQ 941
            .:..|:.:  ..|.||::|:| ....:..:|| |..:|:||.....||||:.||:.|::||||:.
Zfish   602 ALDSPNAEGIRELFCSVSCVTASKDQTVGLSA-APVECNNCKLKLVPQYHIAMSEGSVQNFCTFS 665

  Fly   942 CVMQFQ----NQFARAPL-TLDS-------------DLPPSSAGSS--KSQQQSNRGNKNAAPFP 986
            ||:.:|    |:.|...: |:.|             ..|.||..||  |:...|.:| :|....|
Zfish   666 CVVAYQESLNNKKANTQVNTVTSTSSNTTTAAKTAAPKPASSESSSAAKTSTPSGQG-QNVTKIP 729

  Fly   987 ---------------------------------------------TGLPKRVKL--KLSHTGKGG 1004
                                                         ..|.||||:  :::...:..
Zfish   730 CCQCLNAFFHKPELMEYKRKMYAFCGNDCIDEFRKVNRVVARCENCNLNKRVKVVRRINRVDRSF 794

  Fly  1005 VGGK------------------------KSGSGTMLPVISTVQSLASGETEARIG-------NLT 1038
            ...|                        .|.|.|:      |..:.:|:.|...|       ||.
Zfish   795 CEEKCRALFEQNLVKRWGTKHCSNCFHCNSTSKTV------VTEVFNGKQEEFCGSDCLSQHNLL 853

  Fly  1039 VR--------RKRGRPRES-----------------------GTSSPPLSMPGVHPPAQRGRPRK 1072
            :|        |:..:..||                       |.:...:.........|..:|..
Zfish   854 IRQEIKCSMCRQIKKMNESVKWLGEMKHFCSLRCLMFFCSLQGITGAVIKATSKSLATQCAKPMS 918

  Fly  1073 HAVDYSARSPSP------TMSGGSSHM-GIPVRRN------TTTTMDFGPATVTETKIITVPPYP 1124
            .||....:..:|      ::||.||.. |:....|      |..||                .:.
Zfish   919 SAVTQKPKEATPVIASVVSLSGPSSKQPGVSGNTNAKGSVQTDVTM----------------KHK 967

  Fly  1125 KAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEKDYSNKVLI-PVPVPIFVPQPMYMYSAPFPVP 1188
            :.:|:..:..|..:..:...|.|...|  .:.:||.:.||:: |||||::||.||.:||...|..
Zfish   968 RNLRSQILQNKSPSKNKSTTCKPHTAD--AEIQKDEAPKVIVLPVPVPVYVPVPMNLYSQYVPKS 1030

  Fly  1189 VPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLMMAEMVAE----EKHESDSDS 1249
            |.:|||:|||:|.|||.::|:.|::.|::|::|:|:|||||:|:||||||||    |||.|..|.
Zfish  1031 VGMPLPVPVPLFFPTTLDSAEHIVQTIQEIKEKIPDDPLEADLIMMAEMVAEDAEKEKHISSCDQ 1095

  Fly  1250 DNEIKPDPGLVALQYQNSLESVAQQQQQQQVVDVSGAGHNPYGDDMLQIALKMATGDYDNHHQTS 1314
            .:.|..|..|..|....|.|.  ......|::|.:.....|........|            .|.
Zfish  1096 TDNIMEDLDLQDLSSNLSWEE--DPVSPAQILDQTPEPEPPPPPPPPAPA------------STP 1146

  Fly  1315 TVDLETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQRTARGRKRGVGVVMDPPNRNSR 1379
            |.....:.|.....:.:|                       |...|     .|......|..:||
Zfish  1147 TPTFAPASTPTFAPASTP-----------------------TPTFA-----PVSTPTFAPAPSSR 1183

  Fly  1380 S---PVKRQRGGE--MDHSA-------------LQQQSQQAQQPQEKPDAQ-------------- 1412
            |   .:...:.||  ||..|             ::..|.:.:..::.||..
Zfish  1184 SATMTLVSTKAGEPLMDLEADFPIETIALLREQMENDSGKRRSCKKGPDVSTQKKRGRKCASVPS 1248

  Fly  1413 ---MFLKYTFGVNAWKQWVMTKNA----DIEKSSMRRRPFKTELLQMTADELNYSLCLFVKEVRK 1470
               ..|::.:||.||:.||..|||    |..|...|....|.::|:....||:|.||.|:.|||:
Zfish  1249 NILSKLQHEYGVKAWRDWVRWKNAQPNSDAPKFGSRSMTLKEDVLKCCTAELSYGLCKFITEVRR 1313

  Fly  1471 PNGTEYAPDTIYYLVLGIQQYLYVNGRIDNIFYDPYYERFTECLDEVARKFSVLYNDSQYIVTRV 1535
            |||.:|:||:||||.|||||||:.|.|::|||.|.:|.:|...:..:.:.:......:.||.:||
Zfish  1314 PNGEKYSPDSIYYLCLGIQQYLFENNRMENIFSDVFYTKFCWEMSNILKGWKPTILPNGYIHSRV 1378

  Fly  1536 EEEHLWECKQLGAHSPHVLLSTLMFFNTKHFNLTTVEEHMQLSFSHIMKHWKRSSQNSKVPGSRN 1600
            |||.||.||||||.||.|||:||::|.||:||..|||:|..|||:|: |.:.|...|:||.
Zfish  1379 EEEFLWNCKQLGAFSPGVLLNTLIYFFTKYFNYRTVEQHRLLSFAHV-KRYTRGPANAKVS---- 1438

  Fly  1601 VLLRFYPPQA-----GLDANPRKK-----KVYEQQENEENPLRCPVRLYEFYLSKCPESVKTRND 1655
             .||||||:.     |:.|..|||     :|.:..:|.:|||.|||||||||||||...::....
Zfish  1439 -FLRFYPPKEDSSDDGVPAKKRKKDDERQRVLKIGQNSDNPLHCPVRLYEFYLSKCSPGIRHHAT 1502

  Fly  1656 VFYLQPERSCVPDSPVWYSTQALGQDALQRMLHRVKMVKEINI 1698
            .|||.|||||||.||.|:|..||..:||..||.|:..|:|:::
Zfish  1503 KFYLSPERSCVPSSPTWFSISALSDEALDSMLSRILTVRELHM 1545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
woc	NP_001097946.1	TRASH	684..721	CDD:214799	3/36 (8%)
		zf-FCS	724..762	CDD:283998	14/37 (38%)
		DUF3504	1531..1690	CDD:288835	88/168 (52%)
zmym4.2	XP_005159756.1	THAP	4..93	CDD:214951	7/31 (23%)
		SID-1_RNA_chan	<240..>311	CDD:290673	18/105 (17%)
		zf-FCS	538..580	CDD:283998	10/42 (24%)
		DUF3504	1374..1538	CDD:288835	89/169 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I1702
eggNOG	1	0.900	-	-		E1_2CMKN
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	497	1.000	Inparanoid score	I1345
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266757at33208
OrthoFinder	1	1.000	-	-		FOG0004219
OrthoInspector	1	1.000	-	-		otm24888
orthoMCL	1	0.900	-	-		OOG6_103093
Panther	1	1.100	-	-	O	PTHR45736
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X789
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.830