DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment woc and qrich1

DIOPT Version :9

Sequence 1:	NP_001097946.1	Gene:	woc / 47249	FlyBaseID:	FBgn0010328	Length:	1703	Species:	Drosophila melanogaster
Sequence 2:	NP_001007960.1	Gene:	qrich1 / 493333	XenbaseID:	XB-GENE-1217249	Length:	799	Species:	Xenopus tropicalis

Alignment Length:	820	Identity:	219/820 - (26%)
Similarity:	334/820 - (40%)	Gaps:	233/820 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   943 VMQFQNQFARAPLTLDSDLPPSS----------AGSSKSQQQSNRGNKNAAPFPTGLPKRVKLKL 997
            |.|...|.....|:...::.||:          .||.:||......|::.........:..::::
Frog   144 VQQSPQQVTGQQLSPQLNVHPSNEQPIQVQVQIQGSGQSQTAQTIQNQSLQSQTPSQMQVAQIQV 208

  Fly   998 SHTGKGG---------------------VGGKKSGSGTMLPVISTVQSLASGETEARIGNLTVRR 1041
            .|...|.                     |.|:..|||..      :|..||
Frog   209 QHVQAGQQIQPSDMQDDHIQHQQIQAQLVAGQSVGSGIQ------IQQTAS-------------- 253

  Fly  1042 KRGRPRESGTSSPPLSMPGVHPPAQRGRPRKHAVDYSARSPSPTMSGGSSHMGIPVRRNTTTTMD 1106
                     ..||        ||.|:|.||    :...||       .||.:..||::.....
Frog   254 ---------ALSP--------PPTQQGSPR----EVERRS-------SSSSVLQPVKKRKVDM-- 288

  Fly  1107 FGPATVTETKIITVPPYPKAVRNVNISCKP----LTVTQGEQCS-----PDVRDCATQTEKDYSN 1162
              |.|::..                ||.:|    |.:.||:|.|     ||
Frog   289 --PITLSYA----------------ISGQPVAAVLAIPQGQQQSYVSLRPD-------------- 321

  Fly  1163 KVLIPVPVPIFVPQPMYMYSAPFPVPVPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPL 1227
                     :......::|.|...:..|......:|::....|:.    |.:.......:|.:..
Frog   322 ---------LLTVDSAHLYGATGTITSPTGETWTIPVYSANARSD----LPQQNITHIAIPPEAY 373

  Fly  1228 EAELLMMAEMVAEEKHESDSDSDNEIKPDPGLVALQYQNSLESVAQQQQQQQVVDVSGAGHNPYG 1292
            .|..:..:..||..|.|.:.|.         :|...::..::::|......|.::         |
Frog   374 NAVHVTGSPTVAAVKLEEEKDK---------MVKNTHEEVVQTLANSLFPAQFMN---------G 420

  Fly  1293 DDMLQIALKMATGDYDNHHQTSTVDLETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQ 1357
            :..:.:|::...|.|.|             ||.|:....|.....:.:....|..||.|.
Frog   421 NIHIPVAVQAVAGAYQN-------------TAQTVHIWDPQQQATLHEQVQQHQQQQQHQ----- 467

  Fly  1358 RTARGRKRGVGVVMDPPNRNSRSPVKRQRGGEMDHSALQQQSQQAQQPQEKPDAQMFLKYTF--- 1419
                                                 ||.|:....:||::|..::.|..|.
Frog   468 -------------------------------------LQAQAVNEVEPQQQPSPELLLPSTLKPE 495

  Fly  1420 -GVNAWKQWVMTKNADIEKSSMRRRP---------FKTELLQMTADELNYSLCLFVKEVRKPNGT 1474
             |:..||.|..||||::||.|..|..         |:.:|:.....||||.|||..||.|...|.
Frog   496 EGLQVWKNWAQTKNAELEKDSQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTKEARNMEGE 560

  Fly  1475 EYAPDTIYYLVLGIQQYLYVNGRIDNIFYDPYYERFTECLDEVARKFSVLYNDSQYIV-TRVEEE 1538
            .|..|.:||:.|.||:||..|||:|:||.|.||.:|||.|.||.:.:........|:: :.|.||
Frog   561 PYDADVLYYIFLCIQKYLCENGRVDDIFSDNYYIKFTEWLHEVLKNYQPRVTPIGYVIPSHVTEE 625

  Fly  1539 HLWECKQLGAHSPHVLLSTLMFFNTKHFNLTTVEEHMQLSFSHIMKHWKRSSQNSKVPGSRNVLL 1603
            .||||||||||||..||:||||||||:|.|.||::|::|:||.:::..|::..|   |..::..:
Frog   626 MLWECKQLGAHSPATLLTTLMFFNTKYFLLKTVDQHIKLAFSKVLRQTKKNPSN---PKDKSTSI 687

  Fly  1604 RFYPPQAGLDANPRKK------KVY-EQQENEENPLRCPVRLYEFYLSKCPESVKTRNDVFYLQP 1661
            | |....|:....::|      .:| ||.||.|||||||::||:|||.|||:|||.|||.|||.|
Frog   688 R-YLKALGIHQAGQQKGFSITDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTP 751

  Fly  1662 ERSCVPDSPVWYSTQALGQDALQRMLHRVKMVKEINIALL 1701
            |....|:||:|||||.:.::.:::||.|:.:::||..|::
Frog   752 EPVVAPNSPIWYSTQPISREQMEQMLTRILLIREIQEAIV 791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
woc	NP_001097946.1	TRASH	684..721	CDD:214799
		zf-FCS	724..762	CDD:283998
		DUF3504	1531..1690	CDD:288835	81/166 (49%)
qrich1	NP_001007960.1	DUF3504	624..782	CDD:371846	81/161 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920