Protein Alignment woc and Zmym2

DIOPT Version :10

• Sequence 1: NP_001097946.1
• Gene: woc / 47249
• FlyBaseID: FBgn0010328
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_001386425.1
• Gene: Zmym2 / 305913
• RGDID: 1593255
• Length: 1376
• Species: Rattus norvegicus
• Alignment Length: 1508
• Identity: 388/1508 - (25%)
• Similarity: 604/1508 - (40%)
• Gaps: 358/1508 - (23%)

  Fly   348 EDDSAAAVDATDVSPTTPTDAQAGAKSAATGIAEADGV--AAAANEEEAGGDVPDPDEPTAEESS 410
            |||.    |...:.|..|      ..|:|..:|:...:  .::.|||..|.|      |....||
  Rat    55 EDDD----DVVFIEPVQP------PPSSAPLVADQRPITFTSSKNEELQGND------PKILPSS 103

  Fly   411 SAGAGEPGSTPKIIISWIVGSVQKCKQCGDEKN-CGFRYRSPEESEEMDKEKEND---------K 465
            ...|.:.||..:.|:  |..........|.||| ..|..|.|.|:    |.:.||         :
  Rat   104 KELAPQKGSVSETIV--IDDEEDMETNQGQEKNSSNFIERRPSET----KNRTNDVDFSSSTFSR 162

  Fly   466 AEENA---------EEGEEEEARQKPAAPSGFEYICDTACVDALLEDQPGKYFVRRKKFLVEEVV 521
            ::.||         |...|.:........:|...:.     |..||...|    |....::..|.
  Rat   163 SKVNAGMSNSGITTEPDSEIQIANVTTLETGVSSVS-----DGQLESTDG----RDMNLMITHVT 218

  Fly   522 REEGAAEAEAS---ADGEGGDAEEEATPANTQDCLQCKDKTRCKYFIKQDQDCFYICNDDCFNLL 583
            .....:..::|   .....|...:..||:     |..:.||....|
  Rat   219 SLHNTSLGDSSNGLQSSNFGVNIQTYTPS-----LTSQTKTGVGPF------------------- 259

  Fly   584 NAEEPDKFKLKRHSIRVRNIGATTLQPPQNSPTKRTDGSVVARTVEEAETARLDRIESFRRRCAD 648
               .|.:.          |:.....|..:::|....|..:       :::|...|.:  :::..|
  Rat   260 ---NPGRM----------NVAGDVFQNGESAPHHNPDSWI-------SQSASFPRNQ--KQQGVD 302

  Fly   649 CEADINTDEKQLMWETMDFCNEVCLGSYQ-------RTIGSTCETCKQEVSSIALGKYCVRFGFD 706
            ..:.:.:..||               ::|       :.:..||..||:.:..   |:...:....
  Rat   303 SLSPVASLPKQ---------------NFQPSNQQPTKPVKVTCANCKKPLQK---GQTAYQRKGS 349

  Fly   707 VRQFCCAGCLNTFK---KGLKTCSCCQKDISGGQEGFLAPVGDKDQFKDFCSQSCLRRYESMCNP 768
            ...||...||::|.   ...|.|..|:|||:..:...:|.|...:.|::|||.|||..||...:|
  Rat   350 AHLFCSTTCLSSFSHKPAPKKLCVMCKKDITTMKGTIVAQVDSSESFQEFCSTSCLSLYEDKQSP 414

  Fly   769 RR-KLRTDVCGVCNNQKPVRVEMLLEDREHYFCSNPCFSAFKFVSNVNADPCAMCSKYFERRSAE 832
            .: .|....|.:|.....:|.|:..::..|..||:.||:.::..:.:..:.|..|.:|...:.|.
  Rat   415 AKGALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRMANGLIMNCCEQCGEYLPSKGAG 479

  Fly   833 SYTIYNEQQSPKVFCSRVCINVYIIVNRH------------------------IVSCQWCKVKKY 873
            :..:..:.|. |.||.:.|::.|..|..|                        :.:|..|:.:..
  Rat   480 NNVLVIDGQQ-KRFCCQSCVSEYKQVGSHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCR 543

  Fly   874 NFDMIYQIGGPHDQETLTCSINCLTMHGVSCNISARAVTKCDNCSNFNTPQYHLTMSDASMRNFC 938
            .|||. |..||:......||..|:..|......|......|..|...:.|||..||.|..:.|||
  Rat   544 FFDMT-QCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFC 607

  Fly   939 TYQCVMQFQNQFARAPLTLDSDLPPSSAGSSKSQQQSNRGNKNAAPFPTGL--PKRVKLKLSHTG 1001
            ...||.:||      .|::.|.........|..|.:.|....:....|..|  ..:|....|.|.
  Rat   608 NSSCVAKFQ------ALSMQSSPNGQFVAPSDIQLKCNYCKNSFCSKPEILEWENKVHQFCSRTC 666

  Fly  1002 KGGVGGKK---------------------SGSGTMLPVIST-VQSLASGETEARIGNLTVR---- 1040
            ....  ||                     :.||...|..|. .:.|...:...|:|...|.
  Rat   667 SDDY--KKLHCIVTYCEYCQEEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLGLRCVTCNYC 729

  Fly  1041 ---RKRGRPRE--------------------------------SGTSSPPLSMPGVHPPAQRGRP 1070
               .|:|..:|                                .||....:...|         .
  Rat   730 SQLCKKGATKELDGVVRDFCSEDCCKKFQEWYYKAARCDCCKSQGTLKERVQWRG---------E 785

  Fly  1071 RKHAVDY--------SARSPSPTMSGGSSHMGIPVRRNTTTTMDFGPATVTETKIITVPPYP--- 1124
            .||..|.        ....|:.|...|..::.......|:.|...|.|.         ||.|
  Rat   786 MKHFCDQHCLLRFYCQQNEPNMTTQKGPENLHYDQGCQTSRTKMTGSAP---------PPSPTPN 841

  Fly  1125 KAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEKDYSNK-VLIPVPVPIFVPQPMYMYSAPFPVP 1188
            |.::|..|.|||||:|:...|.|.::..:.||::::..: |.:|:|||::||.||:|||...|||
  Rat   842 KEMKNKAILCKPLTMTKATYCKPHMQTKSCQTDENWKTEYVPVPIPVPVYVPVPMHMYSQSIPVP 906

  Fly  1189 VPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLMMAEMVAEEKHESDSDSDNEI 1253
            ..:|:|:|||:|:|.....::.|...::.::.|:..|||:.|||.|.:|:.||:.::::.:.|.:
  Rat   907 TTVPVPVPVPVFLPAPLENSEKIPASVEDLKSKVSSDPLDTELLTMTDMMTEEEGKTEASNINSV 971

  Fly  1254 KPDPGLVALQYQNSLESVAQQQQQQQVVDVSGAGHNPYGDDM-LQIALKMATGDYDNHHQTSTVD 1317
            ..:..::.    :.|...:....|..:.||      ||..|: ::|....|..:         :|
  Rat   972 IIETDIIG----SDLTKNSDSDIQSNMPDV------PYEPDLDIEIDFPRAAEE---------LD 1017

  Fly  1318 LETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQRTARGRKRGVGVVMDPPNRNSRSPV 1382
            :|.......:             .|..:.:|                        |..|:.:...
  Rat  1018 MENEFLLPPV-------------FGEEYEEQ------------------------PRPRSKKKGT 1045

  Fly  1383 KRQR-GGEMDHSALQQQSQQAQQPQEKPDAQMFLKYTFGVNAWKQWVMTKNAD------IEKSSM 1440
            ||:. .|...|          ....:..:.....|||:||||||.||.|:..|      .|..|.
  Rat  1046 KRKAVSGYQSH----------DDSSDNSECSFPFKYTYGVNAWKHWVKTRQLDEDLLELDELKSS 1100

  Fly  1441 RRRPFKTELLQMTADELNYSLCLFVKEVRKPNGTEYAPDTIYYLVLGIQQYLYVNGRIDNIFYDP 1505
            :....|.:||..|..||||.|..||.|:|:|||..||||:||||.||||:||..:.|.||||.||
  Rat  1101 KSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDP 1165

  Fly  1506 YYERFTECLDEVARKF--SVLYNDSQYIVTRVEEEHLWECKQLGAHSPHVLLSTLMFFNTKHFNL 1568
            .|:.|.:.|:::.|.:  |:|.:.|  |.:||||::||..||||:|||..||:||.:||||:|.|
  Rat  1166 GYQMFEQELNKILRSWQPSILPDGS--IFSRVEEDYLWRIKQLGSHSPVALLNTLFYFNTKYFGL 1228

  Fly  1569 TTVEEHMQLSFSHIMKHWKRSS-----------QNSKVPGSRNVLLRFYPPQAGLDANPRK---- 1618
            .|||:|::|||..:.:|||::.           |.|.:.|:.|        :..:....||
  Rat  1229 KTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVSSLCGTDN--------EDKIATGKRKHEDD 1285

  Fly  1619 KKVYEQQENEENPLRCPVRLYEFYLSKCPESVKTRNDVFYLQPERSCVPDSPVWYSTQALGQDAL 1683
            :.|:||.||..||.||||:::|.||||.|:::..|.||||||||.|...||||||::.:|.::.|
  Rat  1286 EPVFEQVENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSASLDRNTL 1350

  Fly  1684 QRMLHRVKMVKEI 1696
            :.||.||.:||:|
  Rat  1351 ENMLVRVLLVKDI 1363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
woc	NP_001097946.1	MDN1	<7..>419	CDD:444083	18/72 (25%)
		TRASH	684..721	CDD:214799	9/39 (23%)
		zf-FCS	724..762	CDD:428958	15/37 (41%)
		DUF3504	1531..1692	CDD:463430	79/175 (45%)
Zmym2	NP_001386425.1	zf-FCS	326..362	CDD:428958	9/38 (24%)
		zf-FCS	367..408	CDD:428958	15/40 (38%)
		zf-FCS	419..455	CDD:428958	10/35 (29%)
		zf-FCS	461..501	CDD:428958	9/40 (23%)
		zf-FCS	530..569	CDD:428958	11/39 (28%)
		zf-FCS	633..670	CDD:428958	7/36 (19%)
		zf-FCS	721..757	CDD:428958	4/35 (11%)
		zf-FCS	763..798	CDD:428958	6/43 (14%)
		DUF3504	1191..1359	CDD:463430	79/175 (45%)