Protein Alignment woc and Zmym6

DIOPT Version :10

• Sequence 1: NP_001097946.1
• Gene: woc / 47249
• FlyBaseID: FBgn0010328
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_803413.1
• Gene: Zmym6 / 100177
• MGIID: 106505
• Length: 1249
• Species: Mus musculus
• Alignment Length: 1337
• Identity: 249/1337 - (18%)
• Similarity: 398/1337 - (29%)
• Gaps: 523/1337 - (39%)

  Fly   631 AETARLDRIESFRRRCADCEADINTDEKQLMWETMDFCNEVCLGSYQRTIGST------------ 683
            |:...||||    :...|...:....|.:|....:....:..|| :|..:.|:
Mouse    14 AQQGLLDRI----KEEPDDAHEYGPQESELKISAVFSAGDTSLG-FQVGLPSSGPSTSFPAVPAA 73

  Fly   684 ---CETCKQEVSSIALGKYCVRFGFDVRQFCCAGCLNTFKKGL-------KTCSCCQKDISGGQE 738
               |..||:   .:..|:...|.....:.:|..||:..|...:       :||:.|.|||....:
Mouse    74 QVFCFGCKK---LLLKGQPTYRKAGFAQLYCSMGCIIRFSSAVCVPPLPKRTCAHCSKDILNPMD 135

  Fly   739 GFLAPVGDKDQFKDFCSQSCLRRYESMCNPRRKLRTDVCGVCNNQKPVRVEMLLEDREHYFCSNP 803
            .......:....|||||||||..||.                  :|||
Mouse   136 VITTQFENSSLCKDFCSQSCLFSYEL------------------KKPV----------------- 165

  Fly   804 CFSAFKFVSNVNADPCAMCSKYFERRSAESYTIYNEQQSPKVFCSRVCINVYIIVNRHIVSCQWC 868
               ...:.|.::| .|:||.|            ..:..:||        .:|.:.|...:|.:
Mouse   166 ---VTIYTSGISA-KCSMCQK------------GTDNLAPK--------PLYALGNSSRLSAE-- 204

  Fly   869 KVKKYNFDMIYQIGGPHDQETLTCSINCLTMHGVSCNISARAVTKCDNCSNFNTPQYHLTMSDAS 933
                     :.:......:..|.||||||:.:.:...||:.....|.:|.....|||||.||:.:
Mouse   205 ---------MIETTNDSGRTELFCSINCLSAYRIKTVISSGIQVVCHSCKTAAVPQYHLAMSNGT 260

  Fly   934 MRNFCTYQCVMQFQNQFARAPLTLDSDLPPSSAGS---SKSQQQSNRGNKNAA----------PF 985
            :.:||:..||:.|||.|.: |...:|.|.|.|.|.   |...|.:....|:|.          |.
Mouse   261 ICSFCSSNCVLAFQNVFNK-PKGRNSSLAPISQGQEVRSTPVQSAVLARKDAPASSFSSPISNPA 324

  Fly   986 PTGLPKRVK-----------LKLS----------------HTGK--------------------- 1002
            .|.|....|           |||:                :.|:
Mouse   325 ATALETLAKQSHQIALTHLFLKLTCLQCSLLFATKPELLFYKGRMFMFCSKACCDEYKRQNKVKA 389

  Fly  1003 -----------------GGVG----------------GKKSGS--GTMLPVISTVQSLASGETEA 1032
                             .|:.                |::.||  .|....:.|..:....:.|.
Mouse   390 LCDYCKLQKTIEDTVRFSGIDKPFCSEVCKVLSARDFGERWGSYCKTCSYCLQTSANFVENQLEG 454

  Fly  1033 RIG---------------NLTVR----RKRGRPRES-----------------------GTSSP- 1054
            ::.               :.|.|    :::|:..||                       ..:.|
Mouse   455 KLQVFCCEDCMSKFTALLHQTARCDGCKRQGKLSESLKWRGNIKYFCNLFCVLQFCHQYSVNDPI 519

  Fly  1055 PLSMPGVHP-PAQRGRPRKHAVDYSARSP----SPTMSGGSSHMGIPV---RRNTTTTM-DFGPA 1110
            |.....|.| |||...|:......:..||    :|.::..:|...||.   .|||...: ..||.
Mouse   520 PQRKVFVLPKPAQVIIPKAQTAVTALPSPRIATTPVITSVTSLAKIPALQPTRNTNNVLTGAGPT 584

  Fly  1111 TVTETKII-------------TVPPYPKAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEKDYSN 1162
            .|  ||||             .:.| ||.::|..|.|||:|.|:...|.|.....|.||:
Mouse   585 EV--TKIIGNGSAQAPAERLQPLQP-PKLLKNKGILCKPVTQTKATSCRPHTHHAACQTD----- 641

  Fly  1163 KVLIPVPVPIFVPQPMYMYSAPFPVPV------------------------------PIPLPIPV 1197
                       :|.|.:....|...|.                              |.|..:
Mouse   642 -----------LPLPEWKSEEPESPPAKRRRVDFSQTYNAEYIRFGFIICSGSEESSPSPQCV-- 693

  Fly  1198 PIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLMMAEMVAEEKHESDSDSDNEIKPDPGLVAL 1262
                         |..|:...:..||              |:...|.....||.|.||    |..
Mouse   694 -------------ICGEVLPSESVMP--------------VSLSNHLKAKHSDLENKP----VDF 727

  Fly  1263 QYQNSLESVAQQQQ-------QQQVVDVSG------AGHN-----------PYGDDMLQIALKMA 1303
            ..:.|||...|...       ::.:|..|.      |..|           ||..:|....|..:
Mouse   728 FEEKSLEMECQNSSLKKCLLVEESLVKASYLIAFQIAARNKPFSIAEELIKPYLVEMCSEVLGSS 792

  Fly  1304 TGDYDNHHQTSTVDLETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQRTARGRKRGVG 1368
            .|:     :..|:.|..|.....|...|.              |.:..:|
Mouse   793 AGE-----KMKTIPLSNSTIGCRIKKLSD--------------DIEDQLL--------------- 823

  Fly  1369 VVMDPPNRNSRSPVKRQRGGEMDHSALQQQSQQAQQPQEKPDAQMFLKYTFGVNAWKQWVMTKNA 1433
                            |:..|....||     |..:..|..:..:.|.|.       :::.....
Mouse   824 ----------------QKVRESRWFAL-----QVDESSEATEVPLLLCYV-------RFIDYDRG 860

  Fly  1434 DIEKSSMRRRPFKTELLQMTAD--------------ELNYSLCL-FVKEVRKPNGTEYAPDTIYY 1483
            |:::..:    |.||:...:.|              .||::.|: |..:     |.....|..:.
Mouse   861 DVKEELL----FCTEMPSPSTDLEVFELINKYIDSRSLNWNHCVGFCTD-----GAASMTDRYFR 916

  Fly  1484 LVLGIQQYLYVNGRIDNIFYDPYY---ERFTECLDEVARKFSVLY-------NDSQYIVTRVEEE 1538
            |...||:.........:.|....:   ::.:.||.|:..:.|.:.       :|||.:...
Mouse   917 LRSKIQEIAKNTVTFTHCFIHREHLAAKKLSPCLHEILLQSSQILSFVKNSASDSQMLTIL---- 977

  Fly  1539 HLWECKQLGAHSPHV---------------LLSTL--------MFFNTKHFNLTTV---EE---- 1573
                |:::|  |.||               :|:.|        :|.|.||.:|...   ||
Mouse   978 ----CEEMG--SEHVNLPLNAEVRWLSRGRILTRLFELRHEIEIFLNQKHSDLARYFHDEEWIAK 1036

  Fly  1574 --HMQLSFSHIMKHWKRSSQNSKVPGSRNVLLRFYPPQAGLDANPRKKKVYEQQENEENPLRCPV 1636
              ::...||.|.|      .||.:.|:.......|..   :|...::.|::.::..|.:....|
Mouse  1037 LAYLADIFSLINK------LNSSLQGTMTTFFNLYNK---VDVFQKRLKMWLKRAQENDYGMFP- 1091

  Fly  1637 RLYEFYLSKCPESVKTRNDVFYLQPE------RSCVP 1667
             |:..:|.....|||....:.:...|      .:|.|
Mouse  1092 -LFSEFLDSSDVSVKNIASIIFEHLEGLSQIFHACYP 1127

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
woc	NP_001097946.1	MDN1	<7..>419	CDD:444083
		TRASH	684..721	CDD:214799	9/36 (25%)
		zf-FCS	724..762	CDD:428958	15/37 (41%)
		DUF3504	1531..1692	CDD:463430	34/175 (19%)
Zmym6	NP_803413.1	zf-FCS	118..159	CDD:428958	15/40 (38%)