DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fur1 and Rspo3

DIOPT Version :9

Sequence 1:	NP_001262954.1	Gene:	Fur1 / 47220	FlyBaseID:	FBgn0004509	Length:	1478	Species:	Drosophila melanogaster
Sequence 2:	NP_001094460.1	Gene:	Rspo3 / 498997	RGDID:	1563246	Length:	276	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	41/219 - (18%)
Similarity:	73/219 - (33%)	Gaps:	80/219 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   826 YSPQYPRIPP-------------NNFGSSPSGGSKLPLGKVPPPNKSSYVTNNPLLNSAPPKQGY 877
            |..:||.|..             .||.:....|..|.|||              .|:|.|  :|.
  Rat    85 YGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGK--------------CLDSCP--EGL 133

  Fly   878 QQISATYGVI------------------LGKANG-KSNNNSK-----EKTNNKGN---------- 908
            :..:.|...:                  .||..| |....::     :..:.|||
  Rat   134 EASNHTMECVSIVHCEASDWSSWSPCMKKGKTCGFKRGTETRVRDILQHPSAKGNLCPPTSETRT 198

  Fly   909 ------KSNNGNKGKSGGSSGNRKEQTTQSTIIQTSTSKNKYYRISQQQQQKNNKQDRNGVQTQR 967
                  |.:.|.:||.|..  .::::..:....:||:|.:|....|::..:::..::|...|.:|
  Rat   199 CIVQRKKCSKGERGKKGRE--RKRKKLNKEDKKETSSSDSKGLESSRETSEQHESKERQQQQKRR 261

  Fly   968 PKANSGEKSYDEKSRKVVGEITTN 991
            .:         ||.:|.|...|.:
  Rat   262 AR---------EKQQKSVSVSTVH 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fur1	NP_001262954.1	S8_pro-domain	234..309	CDD:293079
		Peptidases_S8_Protein_convertases_Kexins_Fur in-like	332..621	CDD:173789
		Peptidase_S8	363..646	CDD:278510
		P_proprotein	701..787	CDD:279782
		FU	1320..>1350	CDD:214589
Rspo3	NP_001094460.1	Furin-like_2	42..144	CDD:292535	16/74 (22%)
		FU	97..143	CDD:238021	12/61 (20%)
		TSP1	151..202	CDD:214559	7/50 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900