DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fur1 and amon

DIOPT Version :10

Sequence 1:NP_001262954.1 Gene:Fur1 / 47220 FlyBaseID:FBgn0004509 Length:1478 Species:Drosophila melanogaster
Sequence 2:NP_477318.1 Gene:amon / 43215 FlyBaseID:FBgn0023179 Length:654 Species:Drosophila melanogaster


Alignment Length:634 Identity:276/634 - (43%)
Similarity:371/634 - (58%) Gaps:63/634 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   215 GQSGSSGSNNNHIVGH--YTHTWAVHIPNG-DNGMADAVAKDHGFVNLGKIF--DDH-YHFAH-- 271
            |..|.:|.:...:.|.  :|.::.|....| ||..|..||..:||.|||.:.  |.| |||.|  
  Fly    22 GAGGGAGGSGAGLSGPAVFTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRT 86

  Fly   272 --HKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFN- 333
              |..|:|||:    |...|.....||.|.||....|.||.   :||      |:..:..|.|: 
  Fly    87 LPHARSRRSLT----HTRALKSHPAVHTAVQQPGFKRVKRG---LRP------AVPAIHGMKFDL 138

  Fly   334 -------------DSKWPQMWYL-NRG--GG---LDMNVIPAWKMGITGKGVVVTILDDGLESDH 379
                         |..:|..||| |.|  ||   ||:||..||..|||||.|...|:|||::..|
  Fly   139 KVGEGNRIDEEPTDPYFPMQWYLKNTGQNGGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMH 203

  Fly   380 PDIQDNYDPKASYDVNSHDDDPMPHYDMTDS--NRHGTRCAGEVAATANNSFCAVGIAYGASVGG 442
            ||::.||:.:||||.:|:|..|.|.|  ||.  |.|||||||||||..:|..|.||:||.:.:.|
  Fly   204 PDLKFNYNAEASYDFSSNDPFPYPRY--TDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAG 266

  Fly   443 VRMLDGD-VTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGS 506
            :||||.. :||.:||.|:...|..|.||||||||.|||||||||.....||.::|..:||.|.|:
  Fly   267 IRMLDQPYMTDLIEANSMGHEPHKIHIYSASWGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGN 331

  Fly   507 IFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQ-V 570
            |::||||:|| |:|:||||||..|:||:||:||..:|....|.|.||||||:|:|:|.:.... |
  Fly   332 IYVWASGDGG-EEDDCNCDGYAASMWTISINSAINDGQNAHYDESCSSTLASTFSNGAKDPNTGV 395

  Fly   571 VTTDLHHSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPS----WS 631
            .||||:..||.:|:||||:||.|||:.||.|::|..|||||:||:.|.|:|..:|.|..    |:
  Fly   396 ATTDLYGKCTTTHSGTSAAAPEAAGVFALALEANPQLTWRDIQHLTVLTSKRNSLFDAKNRFHWT 460

  Fly   632 RNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTVNHCR 696
            .||||...:|.||:|::||..||.:::.|.:||.:..||.......:.|.....:..::..:.|:
  Fly   461 MNGVGLEFNHLFGFGVLDAGAMVTLSKQWHSVPPRYHCEAGELTQPQAIVMGRSLFWEIKTDACK 525

  Fly   697 ----SVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNS-RSGFNQWPFMSVHTW 756
                .|||||||||.|:..:.||||::|||.||..|...:|:.|.:|:. |.||.:||||:.|:|
  Fly   526 GTDTEVNYLEHVQAVISANASRRGDLELFLTSPMGTKSMILSRRANDDDHRDGFTKWPFMTTHSW 590

  Fly   757 GESPQGNWQLEIHNEGRYMGHALLREWSLIFYGTTQ----SIGPNDPIS 801
            ||.|||.|:||.........|..|.||||:.:||.:    ::.|:.|.|
  Fly   591 GEYPQGTWKLEARFNSPQTRHGNLLEWSLVLHGTKEAPYRTLHPSSPHS 639

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fur1NP_001262954.1 S8_pro-domain 234..309 CDD:465126 31/82 (38%)
Peptidases_S8_Protein_convertases_Kexins_Fur in-lik 332..621 CDD:173789 160/312 (51%)
P_proprotein 701..787 CDD:460225 43/86 (50%)
FU 1320..>1350 CDD:214589
amonNP_477318.1 S8_pro-domain 43..122 CDD:465126 31/82 (38%)
Peptidases_S8_Protein_convertases_Kexins_Fur in-lik 150..446 CDD:173789 159/298 (53%)
Peptidases_S8_S53 <409..485 CDD:415849 38/75 (51%)
P_proprotein 534..621 CDD:460225 43/86 (50%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.