DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Klp54D and AT4G26660

DIOPT Version :9

Sequence 1:	NP_001303355.1	Gene:	Klp54D / 47216	FlyBaseID:	FBgn0263076	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_194396.1	Gene:	AT4G26660 / 828773	AraportID:	AT4G26660	Length:	806	Species:	Arabidopsis thaliana

Alignment Length:	619	Identity:	128/619 - (20%)
Similarity:	223/619 - (36%)	Gaps:	169/619 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 SGKTHTLTGPPDLFVGKPN-----PKDPRHGLIFRSFLYLFQLIKNRKDVNY--VLKASFM--EI 317
            |||...:...||..:.:.|     |.||............|....:.||.|:  .:|.:.|  ..
plant    30 SGKQKPIIQNPDTKIPRSNDENAIPVDPNQKASDHHTALQFTKQSDSKDGNFGEPIKDNKMGQST 94

  Fly   318 YNERVIDLLNPGSARKPLAVR----WSKKSGGFFVENLFTVDCEELDDLLAVL-EEGMRNRAVGS 377
            :.|....||:     .||.|.    .|:::.....|.....|.:.|.|.:..| ||.:|.::.|.
plant    95 FAEDKRSLLD-----SPLKVESRSILSRRTNSVPSEIKEEDDDDSLGDQIRELKEELIRTKSDGY 154

  Fly   378 HAMNDHSSRSHTILTVHILSDQQTDGGVFLSKHGKINFVDLAGSELTKKTMSEGKTL----EEAN 438
            :..:  :|:|.     |...|..:...|.::|...::        ..|:..||||.:    |:..
plant   155 NKAD--ASKSG-----HFARDSLSQLRVSINKSLLMS--------CPKRDESEGKEVIVDGEDVL 204

  Fly   439 NINKSLMVL---------GYCISSLSDSKKRTG--------------HIPYRD--------SQLT 472
            .:||.:..|         .:..:|..::...:|              |..::|        |||.
plant   205 ELNKHIEKLHGSYDSVHSSFASASCYEADSMSGDDEDVCSEDLEKPMHGNHKDVDFVDNDPSQLD 269

  Fly   473 KLLADSLAGNGVTL---MIACV--------SPAHYNHAETLNTL-------RYASRAKRIRTKPV 519
            .:..|: .|:|:::   :.:||        ||...|..:::...       |..|.:..|....|
plant   270 NVEFDT-TGSGISIRSQLPSCVLEEPIFSESPKFKNVQKSVAASTKFSANPRNVSESSNIGDMKV 333

  Fly   520 IKMD---------PREALILSLKRDIHALQMENDHLKAAL--------NLHHQAAPNGGPVENL- 566
            .::.         |.::|..||:|   .||:.:.|..::|        :..|.|.......|||
plant   334 NQISPCMSKKVSGPTDSLAASLQR---GLQIIDYHQGSSLSKSSSVSFSFGHMALKPCAEGENLN 395

  Fly   567 ---LELQLDRVSSGGGVPV-------PKVDLQ-RLPELDGS-----------ELAELVKLYMVEN 609
               ...:.|:.|.||...:       .|||.: .:.|..||           :.|::.:|.::..
plant   396 ASVQSFRKDKASEGGLSSILLCLSCRKKVDQEAEVTEEAGSNEKHLKNMCMEQAAKIEELTLLLR 460

  Fly   610 ESLRQENNHLFTVRETILRDQ--------EIVCRENERLLKKLEDVNKVCVRSPLIPARPAISPT 666
            :|...|:...| ::||....|        .....|.|.|||::.|     ::|.|.|
plant   461 KSDDGEDGTEF-IKETYETKQISEEFGKTNFEVSEKEALLKEIAD-----LKSKLQP-------- 511

  Fly   667 TGKETPGTEIWTNPEPLQSPPGPDLPIEQR----MSENANRRTDTAQKRIDQKRIAKNILIMANA 727
                |..|:...:...|:|       |:.|    :|.|.....|.|::|.....:....:.:.:.
plant   512 ----TKSTDNLRSSLLLRS-------IQMRKSIDVSRNGENSDDLAKEREMWTEMESEWISLTDD 565

  Fly   728 FRKP-DSDITKELNLNPEEAHAKQSTEFMPDMLT 760
            .|.. |:..::..||..|....|.:||.:.|.||
plant   566 LRMDIDNHRSRAENLEFELKQEKLATEELNDALT 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	64/324 (20%)
Klp54D	NP_001303355.1	KISc	166..512	CDD:276812	63/316 (20%)
AT4G26660	NP_194396.1	PLN03188	<129..802	CDD:215621	105/515 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910