Protein Alignment Klp54D and kif17

DIOPT Version :9

• Sequence 1: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_001373250.1
• Gene: kif17 / 557863
• ZFINID: ZDB-GENE-080724-12
• Length: 823
• Species: Danio rerio
• Alignment Length: 636
• Identity: 193/636 - (30%)
• Similarity: 300/636 - (47%)
• Gaps: 128/636 - (20%)

  Fly   165 DNINVVVRVRPLNDKEKRDRHGSTLQFPGNGQVILEGNDVG-----QKRSHNRDSVRVFTYNVVF 224
            :::.||||.||||::||          ..|.::::..:...     :|.....:..:.||::..:
Zfish     4 ESVKVVVRCRPLNNREK----------AMNCKIVVSVDSTHCQCFIKKPGDTEEPPKQFTFDGTY 58

  Fly   225 EPGATQEDILDYSGIKRIIEMGI-EGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGL 288
            ....:.|::  |:.|...:..|: ||::.|.|.||||||||:.|:.|.||       |...| |:
Zfish    59 YINHSTEEV--YNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGVPD-------PPSQR-GI 113

  Fly   289 IFRSFLYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLF- 352
            |.|:|.::|:.|:..::..::::||::|||.|.:.|||.....:|.......::  |.:|.:|.
Zfish   114 IPRAFEHIFETIQCAENTKFLVRASYLEIYKEEIRDLLGKDIKQKMELKEHPER--GVYVRDLTM 176

  Fly   353 -TV----DCEELDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHI-LSDQQTDGGVFLSKHG 411
             ||    :||.:.||      |.|||:||...||..|||||:|.|:|: :....|.|...| :.|
Zfish   177 QTVHSVGECERVMDL------GWRNRSVGYTLMNKDSSRSHSIFTIHLEICSIDTAGDEHL-RAG 234

  Fly   412 KINFVDLAGSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTKLLA 476
            |:|.|||||||...||.:.|..|:||..||.||..||..||:|.|.  |:.:||||||:||:||.
Zfish   235 KLNLVDLAGSERQSKTGATGDRLQEATKINLSLSALGNVISALVDG--RSKYIPYRDSKLTRLLQ 297

  Fly   477 DSLAGNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVIKMDPREALILSLKRDIHAL-- 539
            |||.||..|||:||:|||..|:.|:::|||||:|||.|:.:|.|..||::||:...:.:|..|
Zfish   298 DSLGGNTRTLMVACLSPADNNYEESISTLRYANRAKSIQNRPRINEDPKDALLREYQEEIKKLRA 362

  Fly   540 ----QMENDHLKAALNLHHQAAPNGGPVENLLELQLDRVSSGGGVPVPKVDLQRLPELDGSELAE 600
                |:.:.:|.:.|     |....|....::.......|..      :.:..::.|....:||.
Zfish   363 LISGQLGSGNLSSFL-----AGQKSGEASAVVSRPQSNTSES------EAEKDKIKEEYEKKLAR 416

  Fly   601 LVKLYMVENES---LRQENNHLFTVRETILRDQEIVCRENERLLKKLEDVNKVCVRSPLIPARPA 662
            |...|..|.||   |:::...|.|..||.|                          |.|..:|.:
Zfish   417 LQAEYDAEQESKVKLQEDIAALRTSYETRL--------------------------SSLERSRGS 455

  Fly   663 ISPTTG-------KETPGTEIWTNPEPLQSPPGPDLPIEQRMSENANRRTDTAQK---------- 710
            .:.|||       ||.|.|....:.|..:        |:...||......|...|
Zfish   456 RTHTTGGVHLQQHKEEPITASAASQEQAK--------IDHSESEERPSSVDATVKGAASGESQIL 512

  Fly   711 ---------RIDQKRIAKNILIMANAFRKPDSDITKELNLNPEEAHAKQST 752
                     ::|||...:.:..:...|...:....:||    ::.|.::.|
Zfish   513 DSVVVDIPGQLDQKLALERLQQLEQEFVGGEQVRNEEL----KQRHKQRKT 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	142/366 (39%)
		KISc	166..512	CDD:276812	138/358 (39%)
kif17	NP_001373250.1	Motor_domain	4..335	CDD:419868	140/361 (39%)
		Smc	395..>650	CDD:224117	39/209 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810