Protein Alignment Klp54D and sub

DIOPT Version :9

• Sequence 1: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 170/632 - (26%)
• Similarity: 239/632 - (37%)
• Gaps: 208/632 - (32%)

  Fly   126 SSRNTPYFLRSRENEIGSADTLEIVASKSTGSEECSTPEDNINVVVRVRPLNDKEKRDRHGSTLQ 190
            |...:.|..:|.|...|        ||.:|.:.:.|..|....|.:|:||:.|..|
  Fly    55 SDTESEYKYQSSEATEG--------ASCATSAADSSNVETGPQVFLRLRPVKDASK--------- 102

  Fly   191 FPGNGQVILE--------------GNDVGQKRSHNRDSVRVFTYNVVFEPGATQEDILDYSGIKR 241
                ..::.|              .|:|.:...|       |.:..:|:....|.||.|.....:
  Fly   103 ----AYIVSEEANVLITSCKVDSTSNNVNRMEKH-------FGFTSIFDSTVGQRDIYDTCVGPK 156

  Fly   242 IIEMGIEGFSC-TAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLI---------------F 290
            |:|.     .| |...||.:|||||:||.|           .|.|.|:|               |
  Fly   157 IMEE-----ECVTIMTYGTSGSGKTYTLLG-----------DDVRAGIIPRALENIFTIYQDTVF 205

  Fly   291 RS-----------FL------------------------------------YLFQLIKNRKDVNY 308
            ||           ||                                    ::|: .|...||:.
  Fly   206 RSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFE-TKASTDVSV 269

  Fly   309 VLKASFMEIYNERVIDLL-------NPGSA-RKPLAVRWSKKSGGFFVENLFTVDCEELDDLLAV 365
            ::..||:|||||.|.|||       ..|.. ||.|.:..:|  |..|::.|.:|.....::.|.:
  Fly   270 LVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNK--GHVFIKGLTSVFVTSSEEALRL 332

  Fly   366 LEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGGVFLSKHGKINFVDLAGSELTKKTMSE 430
            |..|.:.....|.::|.:|||||.:.||.||...::.    ::......|.||||||....|.:.
  Fly   333 LRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSG----ITTQSSYKFCDLAGSERVNNTGTS 393

  Fly   431 GKTLEEANNINKSLMVLGYCISSLS--DSKKRTGHIPYRDSQLTKLLADSLAGNGVTLMIACVSP 493
            |..|:||.|||.||||||.|:.:.|  ..||....||||||:||.||..:|.|.....||..|:|
  Fly   394 GLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTP 458

  Fly   494 AHYNHAETLNTLRYASRAKRIRTK-PVIKMDPREALILSLKRDIHALQ----MENDHLKAALNLH 553
            ....:.|.||.|.:||.||.|..| ||||.              |.:.    ||...:...
  Fly   459 LDKYYEENLNVLNFASIAKNIIFKEPVIKQ--------------HRVSYCGFMEFSKMSTC---- 505

  Fly   554 HQAAPNGGPVENLLE-----LQLDRVSSGGGVPVPKVDLQRLPELDGSELAELVKLYMVENESLR 613
                 .||.....||     |||                    |::..:...::::.::| |.||
  Fly   506 -----EGGDYTKELEDENVRLQL--------------------EIEQLKYDHVLQMQLLE-EKLR 544

  Fly   614 QENNHLFTVRETILRDQEIVCRENERLLKKLEDVNKVCVRSPLIPAR 660
                     ||.....|||:  :|.:  |:.||   .|.:..||..|
  Fly   545 ---------RELTATYQEII--QNNK--KQYED---ECEKKLLIAQR 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	129/441 (29%)
		KISc	166..512	CDD:276812	124/432 (29%)
sub	NP_001286548.1	KISc	89..477	CDD:276812	124/430 (29%)
		Kinesin	93..479	CDD:278646	125/428 (29%)
		GBP_C	<512..603	CDD:303769	23/101 (23%)
		coiled coil	576..586	CDD:293879	170/632 (27%)
		coiled coil	592..603	CDD:293879

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940