DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Klp54D and cana

DIOPT Version :9

Sequence 1:NP_001303355.1 Gene:Klp54D / 47216 FlyBaseID:FBgn0263076 Length:760 Species:Drosophila melanogaster
Sequence 2:NP_001027247.1 Gene:cana / 3771934 FlyBaseID:FBgn0040233 Length:1931 Species:Drosophila melanogaster


Alignment Length:637 Identity:166/637 - (26%)
Similarity:280/637 - (43%) Gaps:135/637 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   166 NINVVVRVRPLNDKEKRDRHGSTLQFPGNGQV--ILEGNDVGQKRSHNRDSVRVFTYNVVFEPGA 228
            :|.|.::|||..              ||...:  :.||..:....||    ...:.::.||:.||
  Fly     8 SIQVCIKVRPCE--------------PGLTSLWQVKEGRSIQLADSH----AEPYVFDYVFDEGA 54

  Fly   229 TQEDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLIFRSF 293
            :.:::.|... |.|:...::|.:.|.|.||||.||||:|:.|      .:.||     |::..:.
  Fly    55 SNQEVFDRMA-KHIVHACMQGSNGTIFAYGQTSSGKTYTMMG------DEQNP-----GVMVLAA 107

  Fly   294 LYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLFTVDCEE 358
            ..:||.|.:..:.:::|:..::|||||::.||||    :|...::..:...|     :..|:|:|
  Fly   108 KEIFQQISSETERDFLLRVGYIEIYNEKIYDLLN----KKNQDLKIHESGNG-----IVNVNCKE 163

  Fly   359 L-----DDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGGVFLSKHGKINFVDL 418
            .     ||||..|..|.:.|.||...||:.|||||.|..:.|.|.:.........|...::.|||
  Fly   164 SIVTSEDDLLRQLYMGNKERVVGETNMNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDL 228

  Fly   419 AGSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLS---DSKKRTGHIPYRDSQLTKLLADSLA 480
            ||||          .::.|::.: |||:....:.|||   |||..:    :|||:|.:::..||.
  Fly   229 AGSE----------QVDPADHAS-SLMIFRNLVKSLSESVDSKPNS----FRDSKLPRIMLPSLG 278

  Fly   481 GNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKP-VIKMDPREALILSLKRDIHAL--QME 542
            ||.:|.:|..::|:...  |:.:|:.:.:.||:||.|| |.|:|....::..|.|.|..|  ::.
  Fly   279 GNVLTSIICTITPSFVE--ESSSTISFGTCAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLA 341

  Fly   543 NDHLKAALNLHHQAAPNGGPVENLLEL------------------QLDRVSSGGGVPV---PKVD 586
            ...:|....|..|.. .|....::|::                  .|....|.|..||   |:.:
  Fly   342 KKKIKNESQLVLQEL-EGRIKRDMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPE 405

  Fly   587 LQRLPELDGSELAELVKLYMVENESLRQENNHLFTVRETILRDQEIVCRENERLLKKLEDVNKVC 651
            ..|||.  .|:|..|.|              .||. |..|....:.:|:..:.  |:|:..|   
  Fly   406 ESRLPR--PSKLTNLPK--------------PLFQ-RRGIAPKAKGICKTLKE--KRLQTDN--- 448

  Fly   652 VRSPLIPARPAISPTTGKETPG--TEIWTNPEPLQSPPGPDLPIEQRMSENANRRT--DTAQKRI 712
                 :...|..:...|:||..  ..:..:.:..:|.|..|.|..:..:..|:.:.  :|.:|..
  Fly   449 -----MDTMPGRAKQLGRETASRIPSVMMSKKYQESVPNCDAPQTEISALTASNQVAKETIEKYE 508

  Fly   713 DQ-KRIAKNI--LIMANAFRKPDSDITKELNLNPE-EAHAKQSTEFMPDMLT 760
            :| ||:.:.|  |.|.|.         |.:||..: |.|..:|.:...::|:
  Fly   509 EQVKRLKETIERLEMENG---------KAVNLGEQFETHKAKSKQMEEELLS 551

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klp54DNP_001303355.1 KISc 166..520 CDD:214526 108/364 (30%)
KISc 166..512 CDD:276812 102/355 (29%)
canaNP_001027247.1 KISc 8..316 CDD:214526 108/363 (30%)
Motor_domain 8..310 CDD:277568 104/357 (29%)
SMC_prok_B <471..1270 CDD:274008 21/90 (23%)
Mplasa_alph_rch 924..1647 CDD:275316
CENP-H 1204..>1266 CDD:283493
CALCOCO1 <1489..1850 CDD:285171
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45437891
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.