Protein Alignment Klp54D and Khc

DIOPT Version :9

• Sequence 1: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 670
• Identity: 185/670 - (27%)
• Similarity: 303/670 - (45%)
• Gaps: 163/670 - (24%)

  Fly   157 SEECSTP-EDNINVVVRVRPLNDKEKRDRHGSTLQFPGNGQVILEGNDVGQKRSHNRDSV--RVF 218
            |.|...| ||:|.||.|.|||||.|::......::||.|    :|.|.:         |:  :|:
  Fly     2 SAEREIPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNN----VEENCI---------SIAGKVY 53

  Fly   219 TYNVVFEPGATQEDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKD 283
            .::.||:|.|:||.:.: ...|.|:...:.|::.|.|.||||.||||||:.|    .:|    ..
  Fly    54 LFDKVFKPNASQEKVYN-EAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEG----VIG----DS 109

  Fly   284 PRHGLIFR------SFLYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKK 342
            .:.|:|.|      :.:|..::     ::.:.:|.|:.|||.:::.|||:.....  |:|...|.
  Fly   110 VKQGIIPRIVNDIFNHIYAMEV-----NLEFHIKVSYYEIYMDKIRDLLDVSKVN--LSVHEDKN 167

  Fly   343 SGGF-------FVENLFTVDCEELDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHI----L 396
            ...:       ||.:        .:|:..|:|||..||.:....||:||||||::..:::    |
  Fly   168 RVPYVKGATERFVSS--------PEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENL 224

  Fly   397 SDQQTDGGVFLSKHGKINFVDLAGSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRT 461
            .:|:.     ||  ||:..|||||||...||.:||..|:||.||||||..||..||:|:|..|.
  Fly   225 ENQKK-----LS--GKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKT- 281

  Fly   462 GHIPYRDSQLTKLLADSLAGNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVIKMDPRE 526
             |||||||:||::|.:||.||..|.::.|.|||.:|.:||.:||.:..|||.::....:.   .|
  Fly   282 -HIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVN---EE 342

  Fly   527 ALILSLKRDIHALQMENDHLKAALNLHHQAAPNGGPVENLLELQLDRVSSGGGVPV-PKVDLQRL 590
            ......||.....:.:|..||             |.||. ||::|.|..:|..|.. .:::::.|
  Fly   343 LTAEEWKRRYEKEKEKNARLK-------------GKVEK-LEIELARWRAGETVKAEEQINMEDL 393

  Fly   591 PELDGSEL-------------------------------------AELVKLYMV---ENESLRQE 615
            .|.....|                                     .|..:||..   ::|.:.|:
  Fly   394 MEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLYQQLDDKDEEINQQ 458

  Fly   616 NNHLFTVRETILRDQEIVC---RENERLLKKLEDVNKVCVRSPLIPARPAISPTTGKETPGTEIW 677
            :.:...::|.::..:|::.   ||.|.|..::..:.:                  ..|:...|:
  Fly   459 SQYAEQLKEQVMEQEELIANARREYETLQSEMARIQQ------------------ENESAKEEV- 504

  Fly   678 TNPEPLQSPPGPDLPIEQRMSE--NANRRTDTAQKRIDQKRIAKNILIMANAFRKPDSDITKELN 740
              .|.||:.....:..:|:..|  |.|:..|...:.:.||:         :.|....:::.:
  Fly   505 --KEVLQALEELAVNYDQKSQEIDNKNKDIDALNEELQQKQ---------SVFNAASTELQQ--- 555

  Fly   741 LNPEEAHAKQS-TEFMPDML 759
            |....:|.|:. ||.:.::|
  Fly   556 LKDMSSHQKKRITEMLTNLL 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	132/372 (35%)
		KISc	166..512	CDD:276812	130/364 (36%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	134/368 (36%)
		KISc	12..340	CDD:214526	132/373 (35%)
		Apolipoprotein	595..744	CDD:279749

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437886
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940