Protein Alignment Klp54D and Cenpe

DIOPT Version :9

• Sequence 1: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: XP_038959788.1
• Gene: Cenpe / 362044
• RGDID: 1307115
• Length: 2456
• Species: Rattus norvegicus
• Alignment Length: 633
• Identity: 181/633 - (28%)
• Similarity: 282/633 - (44%)
• Gaps: 134/633 - (21%)

  Fly   164 EDNINVVVRVRPLNDKEKRDRHGSTLQFPGNGQVILEGNDVGQKRSHNRDSVRVFTYNVVFEPGA 228
            |..:.|.|||||||.:|:.....|.:.:..:...|           :..|..:.|.::.||....
  Rat     4 EAAVAVCVRVRPLNSREEELGEASHIYWKTDKNAI-----------YQSDGGKSFQFDRVFHSNE 57

  Fly   229 TQEDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLIFRSF 293
            |.:::.:...:. ||...|:|::.|.|.||||.||||||:.|..|..           |:|.|:.
  Rat    58 TTKNVYEEIAVP-IISSAIQGYNGTIFAYGQTASGKTHTMMGSEDCL-----------GVIPRAI 110

  Fly   294 LYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLFTVDCEE 358
            ..:||.||...:..::|:.|:||||||.:.|||......|||.:|..      ...|::..|..|
  Rat   111 HDIFQRIKKFPEREFLLRVSYMEIYNETITDLLCNTQKVKPLIIRED------INRNVYVADLTE 169

  Fly   359 -----LDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQT-----DGGVFLSKHGKI 413
                 .:..|..|..|.:||..|...||..|||||||..:.:.|.::.     ||.:   |...:
  Rat   170 EVVYTAEMALKWLATGEKNRHYGITKMNQRSSRSHTIFRMILESREKAESSNCDGSI---KVSHL 231

  Fly   414 NFVDLAGSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTKLLADS 478
            |.|||||||...:|.:||..|:|...||::|::||..|..|||.:. .|.|.||||:||::|.:|
  Rat   232 NLVDLAGSERAAQTGAEGMRLKEGCYINRNLLILGQVIKKLSDGQV-GGFINYRDSKLTRILQNS 295

  Fly   479 LAGNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVI-KMDPREALILSLKRDIHALQME 542
            |.||..|.:|..::||..:  |||.||::||.||.::..|.: ::...|||:...:|:|
  Rat   296 LGGNAKTRIICTITPASLD--ETLTTLQFASTAKYMKNTPYVNEVSNDEALLKRYRREI------ 352

  Fly   543 NDHLKAALNLHHQAAPNGGPVENLLELQLDRVSSGGGVPVPKVDLQRLPELDGSELAELVK---- 603
                                |:  |:.||:.|::          ..|..|::..:||:|:.
  Rat   353 --------------------VD--LKKQLEEVNT----------KTRAQEIEKDQLAQLLDEKDL 385

  Fly   604 LYMVENESLRQENNHLFTVRETILRDQEIVCRENERL---LKKLEDVNKVCVRSPLIPARPAISP 665
            |..|::|.: |....:.....:|...||:..::..|:   ..|::|.|  .|:...||..  |:.
  Rat   386 LQKVQDEKI-QNLKRMLVTSSSIALQQELEIKKKRRVTWCFGKMKDSN--YVKEFKIPTN--ITT 445

  Fly   666 TTGKE--TP----------------GTEIWTNP-EPLQ----SPPGPDLPIEQRMSENANRRTDT 707
            .|.|.  ||                .:|::.|. |||.    |.....|..|...||..:..|.
  Rat   446 RTRKTSVTPLRENSLMKLGESALSWESEVFDNTLEPLAEAEWSSATALLSEENLESELTSLNTQ- 509

  Fly   708 AQKRIDQKRIAKNILIMANAFRKPDSDITKELNLNPEEAHAKQSTEFM 755
                      ..|:::.....|:.:.|    |.|..:|.:..:..||:
  Rat   510 ----------YNNLVLDYEQLRRENED----LKLKLKEKNELEEFEFL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	127/363 (35%)
		KISc	166..512	CDD:276812	124/355 (35%)
Cenpe	XP_038959788.1	KISc_CENP_E	6..329	CDD:276825	126/357 (35%)
		Smc	<334..1057	CDD:224117	53/268 (20%)
		Smc	787..1603	CDD:224117
		Smc	1320..2167	CDD:224117

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910