Protein Alignment Klp54D and Kif6

DIOPT Version :9

• Sequence 1: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_796026.2
• Gene: Kif6 / 319991
• MGIID: 1098238
• Length: 802
• Species: Mus musculus
• Alignment Length: 668
• Identity: 180/668 - (26%)
• Similarity: 277/668 - (41%)
• Gaps: 152/668 - (22%)

  Fly   164 EDNINVVVRVRPL----------NDKEKRDRHGSTLQFPGNGQVILEGNDVGQKRSHNRDSVRVF 218
            :..|.:..||:|.          .|::::..|...:..|.:    |....|..||...:     |
Mouse     3 KQTIQIFARVKPTVRKQQQGIYSIDEDEKLTHSLEIVLPRD----LADGFVNNKRESYK-----F 58

  Fly   219 TYNVVFEPGATQEDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKD 283
            .:..:|:..|.||.|.:... |.:.|..:.|::.|.|.|||||||||.|:||..:.:..:
Mouse    59 KFQRIFDQEAKQEIIFEIIA-KPVAESTLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR----- 117

  Fly   284 PRHGLIFRSFLYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNP-GSARK----PLAVRWSKKS 343
               |:|.|:..|:|:.::......|....|::|||||...|||:| ..|.|    |.........
Mouse   118 ---GIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILEDPD 179

  Fly   344 GGFFVENLFTVDCEELDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGGVFLS 408
            ....::||........::.|.:|..|..||.:....||..|:|||.|.|||:.|.:.....|
Mouse   180 QNIHLKNLSLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTVHLSSKEPGSATV--- 241

  Fly   409 KHGKINFVDLAGSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTK 473
            :|.|::.|||||||...||...|..|.||..||.||..|...|.:||: |.|| |||||:|.:|.
Mouse   242 RHAKLHLVDLAGSERVSKTGVGGLLLTEAKYINLSLHYLEQVIIALSE-KHRT-HIPYRNSMMTS 304

  Fly   474 LLADSLAGNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVI--KMDPREALILSLKRDI 536
            :|.|||.||.:|.|||.:|....|..|:::|.|:|.|...|:.:.::  ::|||..::
Mouse   305 VLRDSLGGNCMTTMIATLSLEKRNIDESISTCRFAQRVALIKNEAILNEEIDPRLMIV------- 362

  Fly   537 HALQMENDHLKAALNLHHQAAPNGGPVENLLELQLDRVSSGGGVPVPKVDLQRLPELD------- 594
             .||.|.:.|||.|.:    |......|.|.|.:|        :.:.|:....|.:.|
Mouse   363 -RLQKEIEDLKAELAM----ATGEQRTEALTEAEL--------LQLEKLIASYLEDQDPESRLEV 414

  Fly   595 GSELAELVKLY---------------MVENESLRQENNHLFTVRETILRDQE-------IVCREN 637
            |:::.::...:               .|.:||.||       ..:..|||:|       :..|:|
Mouse   415 GADMRKIHHCFHHFKKLLNDKKTLENTVSSESTRQ-------ACQEPLRDEEYTKLLGLLKQRDN 472

  Fly   638 E-----RLLKKLEDVNKVCVR--------------SPLIPARPAISPTTGKETPGTEIWTNPEPL 683
            |     .:|||.:...:..::              ||.|...||:..|               |.
Mouse   473 EINILVNMLKKEKKKTQDALQNSSLEKSDTRPPQNSPFIAGSPAVPRT---------------PF 522

  Fly   684 QSPPG--PDLPIEQRMSENANRRTDTAQK---------------RIDQKRIAKNILIMANAFRKP 731
            .|.|.  .||.|.:..|...:::|...::               ..|...|..|..::...|.:
Mouse   523 SSAPSHTQDLSICRHRSSLLHKKTGMREEMSLGRQEAFEIFKRDHADSVTIEDNKQVLKQRFSE- 586

  Fly   732 DSDITKELNLNPEEAHAK 749
                .|.|..:..||.:|
Mouse   587 ----AKALGESINEARSK 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	123/368 (33%)
		KISc	166..512	CDD:276812	122/360 (34%)
Kif6	NP_796026.2	KISc_KIF9_like	5..343	CDD:276826	122/360 (34%)
		Kinesin	11..345	CDD:278646	121/356 (34%)
		Cob_adeno_trans	<350..>408	CDD:294596	17/77 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810