Protein Alignment Klp54D and Kif3b

DIOPT Version :9

• Sequence 1: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_032470.3
• Gene: Kif3b / 16569
• MGIID: 107688
• Length: 747
• Species: Mus musculus
• Alignment Length: 592
• Identity: 185/592 - (31%)
• Similarity: 299/592 - (50%)
• Gaps: 91/592 - (15%)

  Fly   165 DNINVVVRVRPLNDKEKRDRHGSTLQFPGN-GQVILEGNDVGQKRSHNRDSVRVFTYNVVFEPGA 228
            :::.||||.||:|.|||...:...:..... |||     .|...:..:.:..:.||::.|::..|
Mouse     8 ESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQV-----SVKNPKGTSHEMPKTFTFDAVYDWNA 67

  Fly   229 TQEDILDYSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLIFRSF 293
            .|.::.|.: .:.:::..::||:.|.|.|||||:|||:|:.|    ..|.|.    :.|:|..||
Mouse    68 KQFELYDET-FRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEG----VRGDPE----KRGVIPNSF 123

  Fly   294 LYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLFTVDCEE 358
            .::|..|...::..|:::||::|||.|.:.|||:....:: |.:: .:...|.:|::|.:...:.
Mouse   124 DHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKR-LELK-ERPDTGVYVKDLSSFVTKS 186

  Fly   359 LDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHI-LSDQQTDGGVFLSKH---GKINFVDLA 419
            :.::..|:..|.:||:||:..||:||||||.|..:.| .|:...||    ..|   ||:|.||||
Mouse   187 VKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDG----ENHIRVGKLNLVDLA 247

  Fly   420 GSELTKKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTKLLADSLAGNGV 484
            |||...||.::|:.|:||..||.||..||..||:|.|.|  :.|||||||:||:||.|||.||..
Mouse   248 GSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGK--STHIPYRDSKLTRLLQDSLGGNAK 310

  Fly   485 TLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVIKMDPREALILSLKRDIHALQMENDHLKAA 549
            |:|:|.|.||.||..|||.|||||:|||.|:.||.:..||::||:...:.:|..|:.:.:.....
Mouse   311 TVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIG 375

  Fly   550 LNLHHQAAPNGGPVENLLELQLDRVSSGGGVPVPKVDLQRLPELDGSELAELVKLYMVENESLRQ 614
            .....:....||             .||||....:.:.:. .|.||.:          :::..|:
Mouse   376 RRKRREKRREGG-------------GSGGGGEEEEEEGEE-GEEDGDD----------KDDYWRE 416

  Fly   615 ENNHLFTVRETILRDQEIVCRENERLL----KKLEDVNKVCVRSPLIPARPAISPTTGKETPGTE 675
            :...|...:..|:.|..:|..|..|||    ||:||:.:....:.::.|:  |.....|...|
Mouse   417 QQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAK--IKAMESKLLVG-- 477

  Fly   676 IWTNPEPLQSPPGPDLPIEQRMSENANRRTDTAQKRIDQKR--IAKNILIMANAFRKPDSDITKE 738
                                  .:|....|:..||.::|||  ||:.        ::.:.:|.::
Mouse   478 ----------------------GKNIVDHTNEQQKILEQKRQEIAEQ--------KRREREIQQQ 512

  Fly   739 LNLNPEE 745
            :....||
Mouse   513 MESRDEE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	141/358 (39%)
		KISc	166..512	CDD:276812	136/350 (39%)
Kif3b	NP_032470.3	KISc_KIF3	8..340	CDD:276822	138/353 (39%)
		Kinesin	15..340	CDD:278646	135/346 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..412		9/61 (15%)
		Globular	580..747
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	698..747

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810