Protein Alignment Men and Me3

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_001402901.1
• Gene: Me3 / 361602
• RGDID: 1311070
• Length: 604
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 303/545 - (55%)
• Similarity: 398/545 - (73%)
• Gaps: 3/545 - (0%)

  Fly   218 GFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLS 282
            |:....:...:||:|||.|||.||||||::|........|:............|||||:.|::|.
  Rat    50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQ 114

  Fly   283 ERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETD 347
            :|||:|||.||:||:...||:|||||||||||.|.|..:..:|:||:|.|||||..:|.:|||.:
  Rat   115 DRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWPEDN 179

  Fly   348 VRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYI 412
            ::|:|||||||||||||||..|||||||||:||||..|:.|.||||:.||||||.|.:|.|||||
  Rat   180 IKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYI 244

  Fly   413 GLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTA 477
            ||:.:|..|..||:.:||||.|...:||.||||||||||||||||||:|||:.:|.|||||||||
  Rat   245 GLKHQRVRGKEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTA 309

  Fly   478 SVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGV 542
            ||||||:||:|:|.|.:|.::..:|.||||||:|||:|.:||::.||:.:.||..:||||||:|:
  Rat   310 SVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAVRKIWMVDSKGL 374

  Fly   543 ITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPI 607
            |.:.|  ..|...|..|||.|..:::|.|.||.|:|..:||.||..|||.::||..||..:|.||
  Rat   375 IVKGR--SHLNHEKEMFAQEHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPI 437

  Fly   608 IFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTY-NNKKFYPGQGNNSYIFPGVALGVLC 671
            ||||||||||||||||:.|..|:||.||||||||..||. :.:.|.||||||:|:|||||||::.
  Rat   438 IFALSNPTSKAECTAEKCYQVTEGRGIFASGSPFKSVTLEDGRTFIPGQGNNAYVFPGVALGIIA 502

  Fly   672 AGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPE 736
            .|:.::|:::||:.||::|:.||:..|::|.||||||:|...|:.||.::::||||:.||:..||
  Rat   503 GGIRHVPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPE 567

  Fly   737 PVNKLAFIKAQMYDLDYPRSVPATY 761
            |.:|.||||:.:|..||......||
  Rat   568 PKDKEAFIKSLIYTPDYDSFSLDTY 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	301/539 (56%)
Me3	NP_001402901.1	PLN03129	9..587	CDD:215594	301/538 (56%)