Protein Alignment Men and Me2

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: XP_006254985.1
• Gene: Me2 / 307270
• RGDID: 1310321
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 278/548 - (50%)
• Similarity: 383/548 - (69%)
• Gaps: 14/548 - (2%)

  Fly   222 LLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRAL-----LARLDQDLDKYMYLISL 281
            :|:.|.:||:|||.:|||.||:.|:||     |..:.:..:||     |.::...|:||:|::.:
  Rat    36 MLNPRTNKGMAFTLQERQMLGLQGLLP-----PKIETQDIQALRFHRNLKKMTSPLEKYIYIMGI 95

  Fly   282 SERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPET 346
            .||||:|||.:|..||..:||:||||||||||.:|..|.:..||:||||.|:||:..::.||||.
  Rat    96 QERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPEN 160

  Fly   347 DVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLY 411
            .|:|:|||||||||||||||..|||||||||.||||.|||:|.:|||:.:||||:..::|:||.|
  Rat   161 HVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFY 225

  Fly   412 IGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGT 476
            :||.::|....|||:.:||||.|...|:|:|.|||||||.|.||||.|.||::.:||||||||||
  Rat   226 MGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLKKYQEKYCTFNDDIQGT 290

  Fly   477 ASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRG 541
            |:||::||||:.::....:.::.:|||||||||||||.|.:::|...||:||||:.:|||.|..|
  Rat   291 AAVALSGLLAAQRVINKPISEHRILFLGAGEAALGIAKLIVISMMESGLSEEEAQRKIWMFDKNG 355

  Fly   542 VITRDRPK--GGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINE 604
            ::.:.|..  ....|...|.|..:.|. |..:||.|::|:|:||.|..|..|...:::.||.|||
  Rat   356 LLVKGRTARIDSNQEPYAHAASENIPA-TFEDAVNKLKPSVIIGVAGAGPLFTPGVIKAMAAINE 419

  Fly   605 TPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPV-TYNNKKFYPGQGNNSYIFPGVALG 668
            .||||||||||::||||||:|||.|:|||:|||||||.|| ..:.:.|.||||||:||||||||.
  Rat   420 RPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVRLQDGRVFTPGQGNNAYIFPGVALA 484

  Fly   669 VLCAGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATV 733
            |:.....:|.:.|||.||:.|...::.::||:|.|||.|::|...|..||.:|.||.|.|.:|..
  Rat   485 VILCEARHISDTVFLEAAKALTSQLTDEELAQGRLYPSLANIQEVSANIAIKIAEYLYANKMAFR 549

  Fly   734 RPEPVNKLAFIKAQMYDLDYPRSVPATY 761
            .|||.:|..::|.:::..:|...:|..|
  Rat   550 YPEPEDKAKYVKERIWRSNYVSLLPDVY 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	276/542 (51%)
Me2	XP_006254985.1	PLN03129	35..573	CDD:215594	276/542 (51%)