DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Men and SPAC750.08c

DIOPT Version :9

Sequence 1:	NP_524880.2	Gene:	Men / 47173	FlyBaseID:	FBgn0002719	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_595034.1	Gene:	SPAC750.08c / 2542710	PomBaseID:	SPAC750.08c	Length:	228	Species:	Schizosaccharomyces pombe

Alignment Length:	174	Identity:	53/174 - (30%)
Similarity:	88/174 - (50%)	Gaps:	18/174 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   569 LAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRC 633
            |..|:..::|.||:|.:.|.|.|.::.:..|:...:.||||.:||||:..|....:...::.|:.
pombe    38 LETAISLIKPTVLLGCSGQPGKFTEKAIREMSKHVKHPIIFPISNPTTLMEAKPVQIDEWSNGKA 102

  Fly   634 IFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCA---------GMLNIPEQVFLVAAERL 689
            :.|:|||..|:|.|.|::...|.||:.::|  ||||.|.         |||.       .|::.|
pombe   103 LMATGSPLPPLTRNGKEYVISQCNNALLYP--ALGVACVLSRCKLLSDGMLK-------AASDAL 158

  Fly   690 AELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATV 733
            |.:.....:|..:|.|.|.:....|..|...:::.|...|::||
pombe   159 ATVPRSLFVADEALLPDLDNAREISRHIVFAVLKQAISEGMSTV 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	53/174 (30%)
		malic	282..463	CDD:278802
		NAD_bind_1_malic_enz	473..750	CDD:133454	53/174 (30%)
SPAC750.08c	NP_595034.1	NADB_Rossmann	<1..222	CDD:304358	53/174 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1122
eggNOG	1	0.900	-	-		E1_COG0281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	1	1.000	-	-		mtm9297
orthoMCL	1	0.900	-	-		OOG6_100205
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710