Protein Alignment Men and mae2

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_587760.1
• Gene: mae2 / 2539592
• PomBaseID: SPCC794.12C
• Length: 565
• Species: Schizosaccharomyces pombe
• Alignment Length: 538
• Identity: 191/538 - (35%)
• Similarity: 293/538 - (54%)
• Gaps: 31/538 - (5%)

  Fly   216 LSGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARL-DQDLDKYMYLI 279
            |.|.|.|...||:|..|||.||||:..|...||.:|....:||:.|......: |:.|.|.:||.
pombe    13 LKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRCYDQYKAIGDEPLQKNLYLS 77

  Fly   280 SLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISI--KDKGHIYDVLKN 342
            .||..|:.|||.::|..:..|:|::||||.|.|.:::|.|::..:|.::.|  .|..:|...|..
pombe    78 QLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDLSYIKQQLSE 142

  Fly   343 WPETD-VRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESIL 406
            :.::| |..|::||.|.|||:||.|..|:.|.|.|..|.|..||:.|::.|||.||||||.|:..
pombe   143 FGKSDSVEYIIITDSEGILGIGDQGVGGVLISVAKGHLMTLCAGLDPNRFLPIVLDVGTNNETHR 207

  Fly   407 EDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFND 471
            ::..|:|||:.|..|:.||.|:|..:.| :|.......|.||||..|||.|:|..||.....|||
pombe   208 KNHQYMGLRKDRVRGEQYDSFLDNVIKA-IREVFPEAFIHFEDFGLANAKRILDHYRPDIACFND 271

  Fly   472 DIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWM 536
            |||||.:||:|.::.:|.:.|:.|.:..::..|||.|.:||||..:..|..:||:.::|:..::|
pombe   272 DIQGTGAVALAAIIGALHVTKSPLTEQRIMIFGAGTAGVGIANQIVAGMVTDGLSLDKARGNLFM 336

  Fly   537 VDSRGV-------ITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQE 594
            :|..|:       |..|..|..|.:.. .|.::......|..|:..|:|.:|:|.:.|.|.|.::
pombe   337 IDRCGLLLERHAKIATDGQKPFLKKDS-DFKEVPSGDINLESAIALVKPTILLGCSGQPGKFTEK 400

  Fly   595 ILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNS 659
            .:..|:...|.||||.:||||:..|...::...::.|:.:.|:|||..|:..|.||:...|.||:
pombe   401 AIREMSKHVERPIIFPISNPTTLMEAKPDQIDKWSDGKALIATGSPLPPLNRNGKKYVISQCNNA 465

  Fly   660 YIFPGVALGVLCA---------GMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSM 715
            .::|  ||||.|.         |||.       .|::.||.:......|..:|.|.|::....|.
pombe   466 LLYP--ALGVACVLSRCKLLSDGMLK-------AASDALATVPRSLFAADEALLPDLNNAREISR 521

  Fly   716 AIAERIVEYAYKNGLATV 733
            .|...:::.|...|::||
pombe   522 HIVFAVLKQAVSEGMSTV 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	191/538 (36%)
mae2	NP_587760.1	PRK13529	1..565	CDD:237414	191/538 (36%)