Protein Alignment Men and Me1

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_036732.3
• Gene: Me1 / 24552
• RGDID: 3074
• Length: 572
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 326/545 - (59%)
• Similarity: 402/545 - (73%)
• Gaps: 3/545 - (0%)

  Fly   218 GFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLS 282
            |:....|...:|.||||.||||||.|||:||..:.....||........||:.|.|:|:.|:.|.
  Rat    15 GYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLLMDLQ 79

  Fly   283 ERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETD 347
            :|||:|||:||.|::...||:|||||||||||:|||..:..:|:||||.|||||..||..|||..
  Rat    80 DRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDV 144

  Fly   348 VRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYI 412
            |:|||||||||||||||||.||||||||||:||||..|:.|.|||||||||||..|.:|:|||||
  Rat   145 VKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYI 209

  Fly   413 GLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTA 477
            |||.||..|..||.|:||||.|...::|.|||||||||||.||||||:|||:.:|||||||||||
  Rat   210 GLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDIQGTA 274

  Fly   478 SVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGV 542
            |||||||||:|:|.|.:|.|.|:||.||||||||||:|.:|||:.|||::|:|:.:||:|||:|:
  Rat   275 SVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEKARQKIWLVDSKGL 339

  Fly   543 ITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPI 607
            |.:.|  ..|||.|..||..||.:..|...|:|::|..|||.||.||||.::||:.||..||.||
  Rat   340 IVKGR--ASLTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPI 402

  Fly   608 IFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTY-NNKKFYPGQGNNSYIFPGVALGVLC 671
            |||||||||||||:|||.|..||||.||||||||.|||. :.:..:||||||||:||||||||:.
  Rat   403 IFALSNPTSKAECSAEECYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVA 467

  Fly   672 AGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPE 736
            .|:.:|.:.|||..||.:::.||...|.:|.|||||::|...|:.||.:||:.|||..:|||.||
  Rat   468 CGLRHINDSVFLTTAEVISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPE 532

  Fly   737 PVNKLAFIKAQMYDLDYPRSVPATY 761
            |.||..|:.:|||..:|.:.:|..|
  Rat   533 PQNKEEFVSSQMYSTNYDQILPDCY 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	324/539 (60%)
Me1	NP_036732.3	PLN03129	11..551	CDD:215594	324/537 (60%)