Protein Alignment Men and Me3

DIOPT Version :9

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_852072.2
• Gene: Me3 / 109264
• MGIID: 1916679
• Length: 604
• Species: Mus musculus
• Alignment Length: 545
• Identity: 303/545 - (55%)
• Similarity: 399/545 - (73%)
• Gaps: 3/545 - (0%)

  Fly   218 GFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLS 282
            |:....:...:||:|||.|||.||||||::|........|:............|||||:.|::|.
Mouse    50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQ 114

  Fly   283 ERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETD 347
            :|||:|||.||:||:...||:|||||||||||.|.|..:..:|:||:|.|||||..:|.:|||.:
Mouse   115 DRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWPEDN 179

  Fly   348 VRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYI 412
            ::|:|||||||||||||||..|||||||||:||||..|:.|.||||:.||||||.|.:|.|||||
Mouse   180 IKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYI 244

  Fly   413 GLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTA 477
            ||:.:|..|:.||:.:||||.|...:||.||||||||||||||||||:|||:.:|.|||||||||
Mouse   245 GLKHQRVRGEEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTA 309

  Fly   478 SVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGV 542
            ||||||:||:|:|.|.:|.::..:|.||||||:|||:|.:||::.||:.:.||..:||||||:|:
Mouse   310 SVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAIKKIWMVDSKGL 374

  Fly   543 ITRDRPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPI 607
            |.:.|  ..|...|..|||.|..:::|.|.||.|:|..:||.||..|||.::||..||..:|.||
Mouse   375 IVKGR--SHLNHEKEMFAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPI 437

  Fly   608 IFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTY-NNKKFYPGQGNNSYIFPGVALGVLC 671
            :|||||||||||||||:.|..|:||.||||||||..||. :.:.|.||||||:|:||||||||:.
Mouse   438 VFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGRTFTPGQGNNAYVFPGVALGVIA 502

  Fly   672 AGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPE 736
            .|:.:||:::||:.||::|:.||:..|::|.||||||:|...|:.||.::::||||:.||:..||
Mouse   503 GGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPE 567

  Fly   737 PVNKLAFIKAQMYDLDYPRSVPATY 761
            |.:|.||:|:.:|..||......||
Mouse   568 PKDKEAFVKSLIYTPDYDSFSLDTY 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	301/539 (56%)
		malic	282..463	CDD:278802	118/180 (66%)
		NAD_bind_1_malic_enz	473..750	CDD:133454	149/277 (54%)
Me3	NP_852072.2	PLN03129	9..587	CDD:215594	301/538 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..50		303/545 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849534
Domainoid	1	1.000	280	1.000	Domainoid score	I1669
eggNOG	1	0.900	-	-		E1_COG0281
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60768
OrthoDB	1	1.010	-	-		D334471at33208
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	1	1.000	-	-		mtm8876
orthoMCL	1	0.900	-	-		OOG6_100205
Panther	1	1.100	-	-	O	PTHR23406
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2182
SonicParanoid	1	1.000	-	-		X340
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.750