Protein Alignment ebo and MSN5

DIOPT Version :9

• Sequence 1: NP_001284739.1
• Gene: ebo / 47141
• FlyBaseID: FBgn0266572
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: NP_010622.1
• Gene: MSN5 / 851935
• SGDID: S000002743
• Length: 1224
• Species: Saccharomyces cerevisiae
• Alignment Length: 1274
• Identity: 220/1274 - (17%)
• Similarity: 428/1274 - (33%)
• Gaps: 452/1274 - (35%)

  Fly     1 MHAASLTTVEGLLQEFYQPSTSNARKREIETNLLAFK--SQPEAWQLCLRVATSSDTTENQFLWF 63
            |.:...:.:...|...|.|.::|::::|.:..|...|  |:...|.  ..:|..:.|  |..|.:
Yeast     1 MDSTGASQIVSALDVIYSPKSNNSQRQEAQKFLDEVKLCSESPFWG--YEIALQNPT--NSILKY 61

  Fly    64 FSTSTLEHTITRRWTQLTSTDKTLLRE----------------------TLWNSYAQLVATPNVA 106
            |....|:|.:.:.|.......:..||:                      |||...|:. ......
Yeast    62 FGLGLLDHAVKKNWNDYDEGKRVALRKWVMELNFGVQDYDTRYIKEKLATLWVEVAKR-TWGEAL 125

  Fly   107 KRHRDTLAQLIALLGKREFPEQDPNYMQHCMELTKTRFQLGINLLKITSEEVVSNRGDLTTEWKQ 171
            |:...|..||:.     .:.:.|.|..: ...:.::..:|.:.:.:|..|:|
Yeast   126 KQTNPTEEQLLT-----SWVDMDNNLFE-LWNINQSSRELALIIFRILFEDV------------- 171

  Fly   172 YFYSCISMCVPDVLDLVTKYLLIAVCHINGKDIQTTIPNTLMDF-------------SLTSALPN 223
              :....:.|...:.::....::.||.|....|:....:....|             .|.:||..
Yeast   172 --FLLDDLIVLKRMTVIQPLCVMIVCPIEVFAIKYKFSDKWTKFKANEEGWFSVWIPELNNALQQ 234

  Fly   224 DNQLSSSILDLLGCVQHLVSWIRTELISEYFLMSIL--DLSQWRPAHEPISLAALSVLNELLYLQ 286
            :|  |..|:.||..::..::|..||:|....::|.|  .||...|..:.::|.::.:|     |.
Yeast   235 NN--SEYIIRLLETLKTCLNWPLTEVIVRNDVLSSLLTCLSSNIPRAQSMALDSIHIL-----LT 292

  Fly   287 KPLPFPGPLMGGVTSLLEQHNNNRRQSEMYSDKFRELLRLYTTKYAAKLMQEPD--------LLE 343
            :|.                  :|....:|..|:..:.:.|..:.|.:.|....|        :::
Yeast   293 RPY------------------SNESHYQMTIDRVFDNMDLLDSVYESLLFDPTDDIDETKYPIIK 339

  Fly   344 TFLNL---LYSCT---TELHGALDFTEKLEIWTP-----IIKGIA-----------QHPAKITRY 386
            .|:::   ||.|.   .|.:|.:....||.:.|.     |:.|:.           ::..|:.:|
Yeast   340 KFVDMISCLYVCVPKIKETNGQIQKYFKLVLKTTYNPSLIVSGLTLDLWCTCLRNDEYLPKLEKY 404

  Fly   387 NNVLTQLVDEIMRRTQFEANK-PELEVLDNELME-----DDTSATEWQQF--------------- 430
              |:..|:       ||.|:. ...|.:|..:.:     |..|.:|:|.|
Yeast   405 --VIPDLL-------QFAADALVYYEQIDGHISKKFAEIDFQSKSEFQTFCSTYRKRIRDIIRLI 460

  Fly   431 ----LDQCFESLALLANTRGAHIVFAQVYNHWSRP--QMYLLS--LEHALDH--GSARSYEAARK 485
                ||..::.|    |.|        :.|::|.|  |..|.|  |:|.|:.  |:...|    .
Yeast   461 SCVELDLTYDWL----NNR--------LNNYFSSPFGQQVLSSTFLDHKLEPYLGALSQY----M 509

  Fly   486 LKGANVGEILR---------DFATVCQAVVRLAPLMDSSTAAPGVADE--MECQLQ-------ML 532
            :....:...:|         |:.....::::...::.:...|..:.:.  ::.|:|       ||
Yeast   510 IVECFINGCIRWKIWYPTGDDYDEKLDSILQKLEILSNQLIALNLREPLLLKKQIQNFALFLTML 574

  Fly   533 SDSLLQTL--QLLASNRL---------------------YSGGSEMDKAT---------FQTDLD 565
            .|::|.||  :::.|..:                     |:.|.|:::..         ...||:
Yeast   575 KDNVLFTLLEKIITSATMDYPEINLEERGAESDAVRDLRYACGIELNRMALLMPESLKKIYPDLE 639

  Fly   566 NLYAQVL--------LAMRSIFPLTKAMSGEELLHRLFAIL--GSIFACNGSLTAASPIVQQAAS 620
            ::.|:::        ::.:|...:....|..::....||.:  ..:.|.:...|..      ..|
Yeast   640 SVIARIMPNLSYHEKISFKSFLLIIVLKSSLDMKEERFAAIVDPELLAWSDKTTVV------GLS 698

  Fly   621 ELLLFISTVIRPKCLLDIPQIQSLLQ-----------------AGSRLGAQLP---------RQV 659
            :|..|:..       |.|.||....|                 .|..|.::|.         |..
Yeast   699 DLHWFMER-------LGIVQIAEYFQRRDIDENSDLLSIPIDDEGKELKSELTKRWQSLFPVRAT 756

  Fly   660 CINVHISLVSYM------------------VLP-----------------WKSVPEQQQEYPR-- 687
            .:.:|.|:.|..                  :||                 ||.:|...|.:.:
Yeast   757 RMFIHYSMQSIKTDEEFKMLQDLWRPRIVPILPYITRLLYQLQSYHDPDNWKGLPTVVQSFVKYS 821

  Fly   688 ---RLWMLREYVQGLAQNFLDLDLGQANESK---------------------------------V 716
               |.|                :.|.:|:||                                 :
Yeast   822 TIERFW----------------EAGASNKSKDEFIDEHMKAMQTLRDFADSVGHIIRYTREYTLL 870

  Fly   717 AATTLSLLGTFTALIEYFKATGGNAKDMLAST---FKPILTKALMIFNNFGQSSIAMAITVAEFS 778
            ..:.:|.||:...|::       .:.|:|.::   |||            |.:.|:..::
Yeast   871 VLSAISSLGSVFYLLD-------ESPDLLLNSIAIFKP------------GSNEISPGVS----- 911

  Fly   779 LSMLRTLPTHLGAQFIKEMITLFISVSSREQLTLSRLAVMEKILQMFKLIVEQPGSA-----SLG 838
                    ||.....:...|...:....::.|.....|.:.|:.::..|::.|..|:     .:.
Yeast   912 --------THGWKHIMNIAIRPILKGCPKDCLGKFMPAFLPKLFEILDLLLCQKWSSHMNDMDMN 968

  Fly   839 LLPSILDFSTQQILP--LLQQQNAATDNSEITSLLYALFDSVLTCKWQ-----FFYKNQLSNGHS 896
            .:|:..|..|::||.  ||:|         :|:::..:   |:.|..|     ...|::|:|...
Yeast   969 PVPTDDDQMTEEILEENLLRQ---------LTTVVVRI---VIDCVGQGNANPNSAKSRLNNHQM 1021

  Fly   897 GGGSGNFNCSDNLHPAHFMAILN----------AYGQMLVSGTDPSNVRSVLFSMQNVNERSRLY 951
            ......||..:.|.|  |:.:||          ::..:||       ::..|.|:.|.|.....|
Yeast  1022 EMRKIIFNDLNTLAP--FLKLLNHLISFKDTKCSFNSILV-------MKCCLTSVLNQNNTVDEY 1077

  Fly   952 QRALFKEQLLASFQRALLNLLLSGEGSLHFDMIAQALYA 990
                |..:::   :..|||:|.:   |...|...:||||
Yeast  1078 ----FTFEVM---KNLLLNVLCN---SAFKDSFHEALYA 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ebo	NP_001284739.1	IBN_N	30..98	CDD:281761	17/91 (19%)
		Xpo1	110..259	CDD:285575	28/161 (17%)
MSN5	NP_010622.1	CRM1	23..>172	CDD:227432	30/174 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900