Protein Alignment ebo and Xpo5

DIOPT Version :9

• Sequence 1: NP_001284739.1
• Gene: ebo / 47141
• FlyBaseID: FBgn0266572
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: NP_001102259.2
• Gene: Xpo5 / 363194
• RGDID: 1311522
• Length: 1204
• Species: Rattus norvegicus
• Alignment Length: 1221
• Identity: 226/1221 - (18%)
• Similarity: 405/1221 - (33%)
• Gaps: 413/1221 - (33%)

  Fly     9 VEGLLQEFYQPST-----SNARKREIETNLLAFKSQPEAWQLC-------LRVATSSDTTENQFL 61
            |..|.:|..:..|     |:.::..:|    |.|...|..:.|       |::|   :.|:...:
  Rat     6 VNALCEELVKAVTVMMDPSSTQRYRLE----ALKFCEEFKEKCPICVPCGLKLA---EKTQIAIV 63

  Fly    62 WFFSTSTLEHTITRRWTQLTSTDKTLLRETLWNSYAQLVATPNVA----KRH-RDTLAQLIALLG 121
            ..|....|||.:..||..::..:|..|:    ||..:|:|...::    :.| :|.|::::..:.
  Rat    64 RHFGLQILEHVVKFRWNSMSRLEKVYLK----NSVMELIANGTLSILEEENHIKDVLSRIVVEMI 124

  Fly   122 KREFPEQDPNYMQHCMELTKTRFQLGINLLKITSEEVVSNRGDLTTEWKQYFYSCISMCVPDVLD 186
            |||:|:..|:.:   |||                 :.:|.:|:...|...:....::..|.....
  Rat   125 KREWPQHWPDML---MEL-----------------DTLSRQGETQRELVMFILLRLAEDVVTFQT 169

  Fly   187 LVTKYLLIAVCHINGKDIQTTIPNTLMDFSLTSALPNDNQLSSSILD-LLGCVQHLVSWIRTELI 250
            |.|:         ..:|||.|:                .|....||: ||..:|        |.:
  Rat   170 LPTQ---------RRRDIQQTL----------------TQNMERILNFLLSTLQ--------ENV 201

  Fly   251 SEYFLMSILDLSQWRPAHE--PISLAALSV---------LNE-------------LLYLQKPLPF 291
            ::|..|. .|.||...|..  .:|:|||:.         ||.             ||..::.|.
  Rat   202 NKYQQMK-TDASQEAEAQANCRVSIAALNTLAGYIDWVSLNHITAENCKLVETLCLLLNEQELQ- 264

  Fly   292 PGPLMGGVTSLL------EQHNNNRRQSEMYSDKFRELLRLYTTKYAAKLMQEPDLLE---TFLN 347
                :|....||      .:..:.:|...::.|     :.::....||:......|:|   .||.
  Rat   265 ----LGAAECLLIAVSRKGKLEDRKRLMILFGD-----VAMHYVLSAAQTADGGGLVEKHYLFLK 320

  Fly   348 LLYSCTTELHG------ALDFTEKLEIWTPIIKGI--------AQHPAKITRYNNVLTQLVDEIM 398
            .|......|..      |||    ..|.||:..|:        ..||::..|.:..:|.  ..:.
  Rat   321 RLCQVLCALGNLLCALLALD----ANIQTPVNFGMYLESFLAFTTHPSQFLRSSTHMTW--GALF 379

  Fly   399 RRTQFEANKPELEVLDNEL-------------MEDDTSATEWQQFLDQCFESLALLANTRGAHIV 450
            |......:...|.|:...|             .:.|:.:.|:.:|
  Rat   380 RHEVLSRDPSLLAVIPKYLRASMTNLVKMGFPSKTDSPSCEYSRF-------------------- 424

  Fly   451 FAQVYNHWSRPQMYLLSLEHALDHGSARSYEAARKLKGANVGEILRDFATVCQ------------ 503
                                  |..|...:.|......|..||::|   .||:
  Rat   425 ----------------------DFDSDEDFNAFFNSSRAQHGEVVR---CVCRLDPKTSFQMAAE 464

  Fly   504 -------AVVRLAPLMDSSTAAPGVAD----------EMECQLQMLSDSLLQTLQLLASNRL-YS 550
                   |.:...|:...|||..|...          :.|.....|...:.|..:.|....| .:
  Rat   465 WLKYQLSAAIDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEAMTFFLESVINQMFRTLEKEELPVN 529

  Fly   551 GGSEMDKATFQTDLDN--LYAQVLLAMRSIFPLT--KAMSGEELLHRLFAIL--GSIFACNGSLT 609
            .|.|:.:.....::.:  :.:.||..:.::||..  |.....::..:||:.:  .|:.......|
  Rat   530 EGIELLQLVLNFEMKDPLILSCVLTNVSALFPFVTYKPAFLPQVFSKLFSFVTFESVGESKAPRT 594

  Fly   610 AASPIVQQAASELLLFISTVIRPKCLLDIPQIQSL------LQAGSRLGAQLPRQVCINVHISLV 668
            .|...|::.|..   .|:.:.|....|.:|....|      |.:...|..|:.:  |     :|:
  Rat   595 RAVRNVRRHACS---SINKMCRDYPDLVLPNFDMLYSHVKQLLSNELLLTQMEK--C-----ALM 649

  Fly   669 SYMVLPWKSVPEQQQEYPRR-------------LWMLREYVQGLAQ-----NFLDLDLGQA---- 711
            ..:||    |..|.::|.|:             :|:..|..:.|:.     .::..||...
  Rat   650 EALVL----VSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRALSDIDAFIAYVGADLKSCDPAA 710

  Fly   712 ------NESKVAATTLSLLG-----TFTALIEYFKATG--------GNAKDMLASTFK-PILTKA 756
                  |.::::....|:||     |:.:.:|..||.|        ||      ..|: |...:.
  Rat   711 QDPCGLNRARMSFCVYSILGVMRRTTWPSDLEEAKAGGFVVGYTPSGN------PVFRNPCTEQI 769

  Fly   757 LMIFNNFGQSSIAMAITVAEFSLSMLRTLPTHLGAQFIKEMITLFISVSSREQLTLSRLAVMEKI 821
            |.:.:|.               |:::||..|    .:..||:|     ...|..|        |.
  Rat   770 LRLLDNL---------------LALVRTHNT----LYTPEMLT-----KMAEPFT--------KA 802

  Fly   822 LQMFKLIVEQPGSASLGLLPSILDFST----QQILPLLQQQNAATDNSEITSLLYALFDSVL--- 879
            |.    |||...:|.|||...:|:.:.    :.||..:|:         ...:||.....:|
  Rat   803 LD----IVESEKTAILGLPQPLLEINDHPVYRTILERMQR---------FFGILYENCYHILGKA 854

  Fly   880 --TCKWQFFYKNQLSNGHSGGGSGNFNCSDNLHPAHFMAILNAYGQMLVSGTDPSNVRSV----- 937
              :.:..|:....|:....|....|.|   |:......::|..:.:.||....|.:..::
  Rat   855 GPSMQQDFYTVEDLATQLLGSAFVNLN---NIPDFRLRSMLRVFVKPLVLFCPPEHYETLISPIL 916

  Fly   938 --LFSMQN---------VNERSRL-----------YQRALFKEQLLASFQRALLNLLLSGEGSLH 980
              ||:..:         :|:||.|           ..:.:.:|||:....|.:::|:
  Rat   917 GPLFTYLHMRLSQKWHVINQRSVLCGEDEIAEDNPESQEMLEEQLVRMLTREVMDLI-------- 973

  Fly   981 FDMIAQALYAMGQVDRRQLLESFVHASLPVAQTSLEEICQTNVLPFIVQDI 1031
                      |.....::..|   |.:.|.|....||:..|.|.|..|.::
  Rat   974 ----------MACCVSKKTAE---HTATPTADGDDEEMMATEVAPSSVVEL 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ebo	NP_001284739.1	IBN_N	30..98	CDD:281761	18/74 (24%)
		Xpo1	110..259	CDD:285575	29/149 (19%)
Xpo5	NP_001102259.2	IBN_N	33..100	CDD:197981	18/73 (25%)
		Xpo1	109..271	CDD:285575	44/220 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900