Protein Alignment ebo and emb

DIOPT Version :10

• Sequence 1: NP_001284739.1
• Gene: ebo / 47141
• FlyBaseID: FBgn0266572
• Length: 1054
• Species: Drosophila melanogaster
• Sequence 2: XP_319051.2
• Gene: emb / 1279344
• VectorBaseID: AGAMI1_012810
• Length: 1053
• Species: Anopheles gambiae
• Alignment Length: 1149
• Identity: 213/1149 - (18%)
• Similarity: 391/1149 - (34%)
• Gaps: 356/1149 - (30%)

  Fly    20 STSNARKREIETNLLAFKSQPEAWQLCLRVATSSDTTENQFLWFFSTSTLEHTITRRWTQL---- 80
            :::..:.|..:|.|...|..|:||   .||.:..:.::||...|::...||..|..||..|
Mosquito    35 NSTGEQLRLAQTVLTTLKEHPDAW---TRVDSILEFSQNQQTKFYALQILEEVIKTRWKILPRNQ 96

  Fly    81 --------------TSTDKTLLRETLWNSYAQLVATPNVAKRHRDTLAQLIALLGKREFPEQDPN 131
                          ||.|..::...               |.:.:.|..::..:.|||:|.....
Mosquito    97 CEGIKKYVVGLIIKTSQDPAMMEAN---------------KVYLNKLNIILVQILKREWPNNWET 146

  Fly   132 YMQHCMELTKTRFQLGIN---LLKITSEEVVSNRGDLTTEWKQYFYSCISMCVPDVLDLVTKYLL 193
            ::...:..:||...|..|   :||:.||||                  ...|...:.....|:|.
Mosquito   147 FISDIVGASKTNETLCQNNMIILKLLSEEV------------------FDFCSGQITQTKAKHLK 193

  Fly   194 IAVCHINGKDIQTTIPNTLMDFSLTSALPNDNQLSSSILDLLGCVQHLVSWIRTELISEYFLMSI 258
            ..:|.      :.....||..|.|.::| |...:|:::..||    ..::||....|   |...:
Mosquito   194 DTMCS------EFAQVFTLCQFVLENSL-NAPLISATLQTLL----KFLNWIPLGYI---FETKL 244

  Fly   259 LDLSQWR----PAHEPISLAALSVLNELLYLQKPLPFPGPLMGGVTSLLEQHNN----NRRQSEM 315
            :|:...|    |....|::..||   |:..||.| .:....:......:||.:.    |...:::
Mosquito   245 IDMLVCRFLTIPMFRNITIMCLS---EIAGLQLP-NYDHVFIALFKQTMEQFDTMIPPNTNMNQI 305

  Fly   316 Y---SDK---FRELLRLYTTKYA---AKLMQEPDLLETFLNLL--YSCTTELHGALDFTEKLEIW 369
            |   ||.   |.:.|.::...:.   |.|:::.|.:|..|..|  ....:|:.....|...||.|
Mosquito   306 YMNGSDDEQCFVQNLAMFLCTFLRVHATLVEKRDTMEVVLKALDYLVMISEVEDVEIFKICLEYW 370

  Fly   370 T----PIIKGIAQHPAKITRYNNVLTQLVDEIMRRTQFEANKPELEVLDN-------ELMEDDTS 423
            .    .:.|.......:.|.|:.:|:::...::.|.   |...|:.|::|       |.|:|..|
Mosquito   371 NSLTGELYKEAHTSSQRRTFYHKILSKVRYIMISRM---AKPEEVLVVENENGEVVREFMKDTNS 432

  Fly   424 ATEWQQFLDQCFESLALLANTRGAHIVFAQVYNHWSRPQMYLLSLEHALDHGSARSYEAARKLKG 488
                                        ..:|.:.....:||..|::| |.....:.:...::.|
Mosquito   433 ----------------------------INLYKNMRETLVYLTHLDYA-DTERIMTDKLNNQVNG 468

  Fly   489 ANVGEILRDFATVCQAVVRLAPLMDSSTAAPGVADEMECQLQMLSDSL--------LQTLQLLAS 545
            :...  .::..|:|.|:       .|.:.|....||....:.::.:.|        .....::||
Mosquito   469 SEFS--WKNLNTLCWAI-------GSISGAFFEEDEKRFLVTVIKELLGLCEHKKGKDNKAIIAS 524

  Fly   546 NRLYSGGSEMDKATFQTDLDNLYAQVLLAMRSIFPLTKAMSGEELLHRLFAILGSI------FAC 604
            |.:|..|.              |.:.|   |:.:...|.     ::::||..:...      .||
Mosquito   525 NIMYVVGQ--------------YPRFL---RAHWKFLKT-----VVNKLFEFMHETHDGVQDMAC 567

  Fly   605 NG----SLTAASPIVQQAASELLLFISTVIRPK----CLLDIPQIQSLLQA-GSRLGAQLPRQVC 660
            :.    :|......||...:|...||..::...    |.|...|:.:..:| |..:.||..:
Mosquito   568 DTFIKIALKCRRHFVQLQPNESCTFIEEILATMSSIICDLQPQQVHTFYEAVGYMISAQADQ--- 629

  Fly   661 INVHISLVSYMVLP---WKSVPEQQQEYPRRLWMLRE------------------------YVQG 698
            :...|.:..||:||   |..:..|.   .:.:.:|::                        ||..
Mosquito   630 VQQDILIEKYMMLPNQVWDDIISQA---TKNVDILKDMGAVKQLGSILKTNVRACKALGHSYVSQ 691

  Fly   699 LAQNFLDL---------DLGQA---------NESKVAATTLSLLGTFTALIEY-FKATGGNAKDM 744
            |.:.:||:         ::.||         |:..:.|..:....|.|.:.|: :|:   |...|
Mosquito   692 LGRIYLDMLNVYKIMSENITQAISLNGLSINNQPLIKAMHVVKKETLTLISEWVWKS---NDPKM 753

  Fly   745 LASTFKPILTKALMIFNNFGQSSI----------AMAITVAEFSLSMLRTLPTHLGAQF--IKEM 797
            :...|.|.|.:|::.  ::.::.:          .||..|......:...:|....|.|  ..:|
Mosquito   754 VMENFIPPLLEAVLF--DYQRTKVPNAREPLVLSTMASIVNRLQAVITPEIPKIFDALFDCTLDM 816

  Fly   798 IT--------------------------LFISVSSREQLTLSRLAVMEKILQMFKLIVEQPGSAS 836
            |.                          .|:|:.. ||..|    |.:.|:..||..:.......
Mosquito   817 INKNFEDYPQHRTNFYELLQAVNMYCFKAFLSIPP-EQFKL----VFDSIVWAFKHTMRNVADTG 876

  Fly   837 LGLLPSILD------------FSTQQILPLLQQQNAATDNSEITSL---------LYALF----- 875
            |.:|..:|.            :.|.....|:|..:..||.|...||         :::|.
Mosquito   877 LNILMQMLQNLEQHPQAAQSFYQTYYTDILMQIFSVVTDTSHTASLQNHATILAYMFSLVEAGRI 941

  Fly   876 --------DSVLTCKWQFFYKNQLSNGHSGGG------SGNFNCSDNLHPAHFMAILNAYGQML- 925
                    |:||..:.......:.:..|..|.      :|.||...::|         |:.:.|
Mosquito   942 TVKLGPSDDNVLNIQEYVAMLLKSAFSHLTGNQIKIFVTGLFNLDQDVH---------AFKEHLR 997

  Fly   926 --------VSGTDPSNVRSVLFSMQNVNERSRLYQRALFKEQLL 961
                    |:|.|.|:    |:..:..||..::.:.   |.::|
Mosquito   998 DFLIQIKEVTGEDDSD----LYLEERENELKKIQEE---KRRML 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ebo	NP_001284739.1	CRM1	12..>368	CDD:227432	81/387 (21%)
		IBN_N	29..98	CDD:197981	20/86 (23%)
emb	XP_319051.2	CRM1	13..1032	CDD:227432	212/1145 (19%)