Protein Alignment dup and Cdt1

DIOPT Version :10

• Sequence 1: NP_524878.1
• Gene: dup / 47121
• FlyBaseID: FBgn0000996
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001099662.1
• Gene: Cdt1 / 292071
• RGDID: 1309211
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 579
• Identity: 182/579 - (31%)
• Similarity: 280/579 - (48%)
• Gaps: 135/579 - (23%)

  Fly   168 SPIKADLRRQLTFDEVKTKVSRSAKLQELKAVLALKAALEQKRKEQEERNRKLRDAGPSPSKSKM 232
            ||:|......::....::||.....:.||::.|                 |:.|..|......:.
  Rat   106 SPVKRTKSTTVSRGPQQSKVPSQDSISELQSCL-----------------RQARKLGAQARALRA 153

  Fly   233 SVQLKEFDTIELEVLISPLKTFKTPTKIPPPTPDKHELMSPRHTDVSKRLLFSPAKNGSPVKLVE 297
            .||                     ...:.|.|||..|.......|                   :
  Rat   154 RVQ---------------------ENVVEPSTPDTKEPTEQPCVD-------------------K 178

  Fly   298 VPAYKRYASLVESSRAGQLPLPYKYRHLLDVFKGLDSVVAMFHNRKETITFKKLKPAVQRMLRKN 362
            .|||:|:.:|.:....| |.|||||:.|.::|:.:|::|:|.|||.||:||.|:|..||.|:||.
  Rat   179 APAYQRFHALAQPGLPG-LVLPYKYQVLAEMFRSMDTIVSMLHNRSETVTFAKVKQGVQEMIRKR 242

  Fly   363 FTETHLAQIKHIYPDAFIFSQ---VKTRNFGSVSKADYFQLIIAPNVEPLPEQQQSEKPQHFTKI 424
            |.|.::.|||.:||:::.|.|   |.|.. .|:.::|| ||    .:|||..|:
  Rat   243 FEERNMGQIKTVYPESYSFRQECNVPTFK-DSIKRSDY-QL----TIEPLLGQE----------- 290

  Fly   425 NEDDVLASAQSTSMNPHVMTARMQRFQSLLLDRAMRAHDQFLRSQDPPIII-EKALTRWHPQFDL 488
                   :..:|.:....:..|.|.|:..|::|....|..||.|.:||:.: |..||||||:|::
  Rat   291 -------AGGATQLTATGLLQRRQVFRQNLVERVKEHHKVFLASLNPPMTVPEDQLTRWHPRFNV 348

  Fly   489 ESCPEVELSPLPQPPNVEKYSSAKDILSTARNLFNCATP-MERAMDRYEAKLESEKQQAAESNKK 552
            :..|::|.:.|||||..||.::|:::|:.||||.   || ||:|:
  Rat   349 DEVPDIEPAELPQPPVTEKLTTAQEVLARARNLM---TPKMEKAL-------------------- 390

  Fly   553 TEEQQAGEVTRTSTAIQTSQEVPGISGSSKNPTVPETTNQTETAKPTVKDCTVPDASSNLLKGLP 617
                       ::.|:::::  ||..|:| :|.:|.|           ...|.|.||.:.|||:.
  Rat   391 -----------SNLALRSAE--PGSPGTS-SPALPAT-----------PPATPPAASPSALKGVS 430

  Fly   618 KSLIEKIRAKQAAKALEAMTRRPSQDQEATKYSRLPELARHLRNVFVTERKGVLTLEVIIKKIQN 682
            ::|:|:||||:..|.|..|||.|.::....:..|||||||.||.|||:|||..||:||:..::.:
  Rat   431 QALLERIRAKEVQKQLARMTRCPEKELRLQRLERLPELARVLRGVFVSERKPALTMEVVCARMVD 495

  Fly   683 SFRANLTPQEIEAHLKLLAKELPSWASFHEVRKTMYLKVAKDMDMNKIIEKLESVANAK 741
            |.||.|:|.|:|.||.|||:.||.|.|.|.||...|:|:.|..|:..:..||....:|:
  Rat   496 SSRAALSPGEMEKHLLLLAELLPDWLSLHRVRTDTYVKLDKAADLAGLTAKLARQVHAE 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dup	NP_524878.1	CDT1	318..500	CDD:462618	66/185 (36%)
		Cdt1_c	610..735	CDD:176572	58/124 (47%)
Cdt1	NP_001099662.1	Cdt1_m	180..363	CDD:176571	76/207 (37%)
		Cdt1_c	426..548	CDD:176572	58/121 (48%)