Protein Alignment comt and MSP1

DIOPT Version :10

• Sequence 1: NP_524877.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_011542.3
• Gene: MSP1 / 852915
• SGDID: S000003260
• Length: 362
• Species: Saccharomyces cerevisiae
• Alignment Length: 395
• Identity: 113/395 - (28%)
• Similarity: 177/395 - (44%)
• Gaps: 68/395 - (17%)

  Fly   117 MAKEF-IMQFAGMALTVGQSLVFNFKDKKLLG------LAVKSLEAIDPKSLGEGKDTAMRNVRF 174
            |:::| :.....:::.||..:...:...:||.      |:.||.|:...:||
Yeast     1 MSRKFDLKTITDLSVLVGTGISLYYLVSRLLNDVESGPLSGKSRESKAKQSL------------- 52

  Fly   175 GRILGNTVVQFEKAENSSLNLQG---KSKGKVVRQSIINPD-WDFGKMGIGGLDKEFNSIFRRAF 235
                     |:||....|..|..   .:..:.:..||:.|| .:.....|||||...:.:..
Yeast    53 ---------QWEKLVKRSPALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHE--- 105

  Fly   236 ASRVFP---PELVEQLGCKHV-KGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVG 296
             |.::|   ||:......... .|:|||||||.|||::|:.:.....|....| ....|:||:.|
Yeast   106 -SVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISI-RMSSIMDKWYG 168

  Fly   297 ESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLLTKIDGV 361
            ||...|..:|:.|    .:|.|    .||..||||:..::|.|.  :..|..|:..:.:|..||:
Yeast   169 ESNKIVDAMFSLA----NKLQP----CIIFIDEIDSFLRERSST--DHEVTATLKAEFMTLWDGL 223

  Fly   362 DQLNN--ILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDV 424
              |||  :::||.|||.:.||:|.||  ||..:..:|||....|.:||::   .:::.....|:.
Yeast   224 --LNNGRVMIIGATNRINDIDDAFLR--RLPKRFLVSLPGSDQRYKILSV---LLKDTKLDEDEF 281

  Fly   425 DNKEIAALTKNFSGAELEGLVRAAQSSAMNRLIKADAKV----TVDPEAMEKLKV---NRDDFLH 482
            |.:.||..||.|||::|:.|.|.|...|....||...::    |:|......||:   ...||..
Yeast   282 DLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQLIDSGTIDVNDTSSLKIRPLKTKDFTK 346

  Fly   483 SLEHD 487
            .|..|
Yeast   347 KLRMD 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_524877.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011	10/47 (21%)
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	62/181 (34%)
		CDC48	<220..>606	CDD:273521	92/281 (33%)
		SpoVK	<526..702	CDD:440232
MSP1	NP_011542.3	RecA-like_ATAD1	92..255	CDD:410928	62/181 (34%)
		AAA_lid_3	280..319	CDD:465537	15/38 (39%)