DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment comt and Fignl2

DIOPT Version :9

Sequence 1:	NP_001259506.1	Gene:	comt / 47091	FlyBaseID:	FBgn0000346	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001201840.1	Gene:	Fignl2 / 668225	MGIID:	3646919	Length:	644	Species:	Mus musculus

Alignment Length:	202	Identity:	58/202 - (28%)
Similarity:	95/202 - (47%)	Gaps:	29/202 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 ILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANVRRLFAEAEEEEKRLGPNS 320
            :|.:||.|.||.|:.|.:.|.|.|...:: .|..:......|....::..||.|     |..|.:
Mouse   423 VLFFGPRGCGKALLGRCLATRLGATLLRL-RGAGLAASGAVEGARLLQAAFAAA-----RCRPPA 481

  Fly   321 GLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLLTKIDGV--DQLNNILVIGMTNRRDMIDEAL 383
               :::..|:||:...|...|       ::...|||.:||.  .:.:.:||:|.|:|...:|||.
Mouse   482 ---VLLISELDALLPARDDGA-------SLRAPLLTCLDGSCGARADGVLVVGTTSRPAALDEAT 536

  Fly   384 LRPGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIAAL---TKNFSGAELEGLV 445
            .|  |..::..::||:...|.|||      .|...:....::.:|:|||   |:.|||.||..|.
Mouse   537 RR--RFALRFYVALPDGAARGQIL------QRALAQQGCALNERELAALVQGTQGFSGGELGQLC 593

  Fly   446 RAAQSSA 452
            :.|.:.|
Mouse   594 QQAAAEA 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011
		SpoVK	242..699	CDD:223540	58/202 (29%)
		AAA	256..397	CDD:278434	38/142 (27%)
		AAA	539..668	CDD:278434
Fignl2	NP_001201840.1	SpoVK	<381..638	CDD:223540	58/202 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900