Protein Alignment comt and FIGN

DIOPT Version :9

• Sequence 1: NP_001259506.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_011509691.1
• Gene: FIGN / 55137
• HGNCID: 13285
• Length: 785
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 88/333 - (26%)
• Similarity: 146/333 - (43%)
• Gaps: 63/333 - (18%)

  Fly   186 EKAENSSLNLQGKSKGKVVRQSIINP--DWDFGKMGIGGLDKEFNSIFRRAFASRVFPPELVEQL 248
            |:.:|:..:|......:::.|   .|  ||:    .|.|||     :.:......|..|.|....
Human   485 EQLKNTDTHLIDLVTNEIITQ---GPPVDWN----DIAGLD-----LVKAVIKEEVLWPVLRSDA 537

  Fly   249 --GCKHV-KGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANVRRLFAEAE 310
              |...: :.|||:||.||||||:.|.|.:.|.|...||. |..::.|::||:|..:...|..|.
Human   538 FSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIA-GSGLVAKWLGEAEKIIHASFLVAR 601

  Fly   311 EEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVV---NQLLTKIDGV-----DQLNNI 367
            ..:    |:    :|...:||.:...:.:..     |..|.   .:.|.::|.|     ||   |
Human   602 CRQ----PS----VIFVSDIDMLLSSQVNEE-----HSPVSRMRTEFLMQLDTVLTSAEDQ---I 650

  Fly   368 LVIGMTNRRDMIDEALLR--PGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIA 430
            :||..|::.:.|||:|.|  ..||.:.:..|....|..||:|:.|          |..:::||.|
Human   651 VVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQH----------NYCLNDKEFA 705

  Fly   431 AL---TKNFSGAELEGLVRAAQSSAMNRLIKADAKVTVDPEAMEKLKVNRDDFLHSLEHDIKPAF 492
            .|   |:.|||.::..|.:.|....::.:...|.. .:.|..:.  .|...||.::. ..|:|:.
Human   706 LLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLS-AIMPSQLR--PVTYQDFENAF-CKIQPSI 766

  Fly   493 GTAQEILD 500
              :|:.||
Human   767 --SQKELD 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011
		SpoVK	242..699	CDD:223540	76/275 (28%)
		AAA	256..397	CDD:278434	46/150 (31%)
		AAA	539..668	CDD:278434
FIGN	XP_011509691.1	AAA	545..680	CDD:214640	46/151 (30%)
		AAA	548..678	CDD:278434	46/146 (32%)
		Vps4_C	<749..782	CDD:286426	8/27 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810