Protein Alignment comt and nvl

DIOPT Version :9

• Sequence 1: NP_001259506.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_998649.1
• Gene: nvl / 406805
• ZFINID: ZDB-GENE-040426-2871
• Length: 796
• Species: Danio rerio
• Alignment Length: 565
• Identity: 146/565 - (25%)
• Similarity: 244/565 - (43%)
• Gaps: 130/565 - (23%)

  Fly   184 QFEKAENSSLNLQGKSKGKVVRQSIINPDWDFGKMGIGGLDKEFNSIFRRAFAS----------- 237
            :.|| |..|:..:.:.|.|:...|..:......|..:.|.:.:|:|:....|..
Zfish   179 RLEK-EKKSVKQKRQKKNKLEEDSETSAGVPAKKSKVKGFELQFSSVKFEDFGGSDETLEEVCKL 242

  Fly   238 --RVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIG-----TMLNAREPKIVNGPQILDKYV 295
              .:..||:.::||....:|.||:||||.||||:|:.:.     .:|....|::|:|..
Zfish   243 LIHMRHPEVYQRLGVVPPRGFLLHGPPGCGKTLLAQAVAGETALPLLKISAPELVSGVS------ 301

  Fly   296 GESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLLTKIDG 360
            ||||..:|.||.:|        .:|...|:..||||||..:|.:  .:..:...:|.||||.:|.
Zfish   302 GESEQKLRELFEQA--------ISSAPCILFIDEIDAITPKRET--ASKDMERRIVAQLLTCMDD 356

  Fly   361 VDQL---NNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKIND 422
            ::.:   ..:||||.|||.|.:|.||.|.||.:.::.:.:|:|..|::||....:::|    :.|
Zfish   357 LNSMLEPAQVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEGARMKILKTLCRKIR----LPD 417

  Fly   423 DVDNKEIAALTKNFSGAELEGLVRAAQSSAMNRLI--------------------KADAKVTVDP 467
            |.|.:.:|.||..:.||:|..|.|.|..:|:||::                    ...:.|::..
Zfish   418 DFDFRHLARLTPGYVGADLMALCREAAMNAVNRILLEPTTEDQITPTLALARLLDLLKSSVSLSE 482

  Fly   468 EAMEKLKVNRDDFLHSLEHDIKPA-----FGTAQEILDNMLARGVINWG---------------- 511
            :.:..|.|...||..||.. ::|:     |.|..:          :.|.
Zfish   483 DQLAALCVLMSDFSSSLVR-VQPSAKREGFATVPD----------VTWADVGALQDVREELHMAI 536

  Fly   512 -APVSNLLEDGMLYVQQAKAPESSGLVSVLVAGAPNSGKTALAAQLAKMSDFPFVKVCSPEDM-- 573
             ||:.|        .:|.||...|....:|:||.|..|||.||..:|..|...|:.|..||.:
Zfish   537 MAPIQN--------PEQFKALGLSAPAGLLLAGPPGCGKTLLAKAVANASGLNFISVKGPELLNM 593

  Fly   574 -VGYTESAKCLHIRKIFDDAYRSMLSCIVVDNVERLLDYGSIGPR----YSNMTLQALLVLLKKQ 633
             ||.:|.|    :|::|.....|....|..|.::.|.      ||    .|..:::.:..||.:.
Zfish   594 YVGESERA----VRQVFQRGRNSAPCVIFFDEIDALC------PRRSEHESGASVRVVNQLLTEM 648

  Fly   634 P--PKGRKLLILCTSSRREVLEEMEMLTAFTSVLHVPNLSKPDHV 676
            .  ...|::.|:..::|.::::        .:||....|.|..:|
Zfish   649 DGMENRRQVFIMAATNRPDIID--------PAVLRPGRLDKTLYV 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011
		SpoVK	242..699	CDD:223540	134/494 (27%)
		AAA	256..397	CDD:278434	52/148 (35%)
		AAA	539..668	CDD:278434	35/137 (26%)
nvl	NP_998649.1	Nucleolin_bd	2..71	CDD:293330
		RNA_polI_A34	<165..215	CDD:285426	8/36 (22%)
		SpoVK	246..792	CDD:223540	134/497 (27%)
		AAA	264..395	CDD:278434	52/146 (36%)
		P-loop_NTPase	537..>573	CDD:304359	16/43 (37%)
		AAA	557..687	CDD:278434	38/147 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900