Protein Alignment comt and CG14183

DIOPT Version :9

• Sequence 1: NP_001259506.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Alignment Length: 638
• Identity: 121/638 - (18%)
• Similarity: 226/638 - (35%)
• Gaps: 169/638 - (26%)

  Fly   138 FNFKDKKLLGLAVKS-------LEAIDPKSLGEGKDTAMRNVRFGRILGNTVVQFEKA-----EN 190
            |.||..:.:.:.||.       |:|          |.:..|:.....:.:|.:..|:|     .|
  Fly   202 FTFKPDQAMSIPVKRTIFSADFLKA----------DESCENLIKKDDVADTAIDDEEALSAIQNN 256

  Fly   191 SSLNLQGKSKG----KVVRQSIINPDWDFGKMGIGGLDKEFNSIFRRAFASRVFPPELVEQLGCK 251
            ::..:|...:|    |:|:                         .|:.|...::        |.|
  Fly   257 AACKIQSCWRGYKTRKIVK-------------------------IRKRFKEELY--------GMK 288

  Fly   252 HVKGILLYGPPGTGKTLMARQIGTMLNAR-EPKIVN-------------GPQILDKYVGESEANV 302
            .::  .|..|..|..::|......||..: :...:|             .|.:::    :...::
  Fly   289 KIR--KLKRPNQTANSIMEMYKNEMLKKKLDEDFINLINDERTRLLQFRSPWMME----DISDHI 347

  Fly   303 RRLFAEAEEEEKRLGP-----NSGLHIIIFDEI-------DAICKQRGSVAGNSGVHDTVVNQLL 355
            |..|.|..:......|     ..|..:::.||.       :::.|:..|.|....:.|....:..
  Fly   348 RAWFKEFYDATGNFHPYPDPVKQGTVLVVIDETMTPMEFQESLGKKPLSKAELKKLRDKEKKEKR 412

  Fly   356 TKIDGVDQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRV-QILNIHTKRMRE--- 416
            .|.:.:.||.    :....||..:.:|    |.:::..|::.......: :.:..::|..|.
  Fly   413 KKKEKLKQLK----MKEAKRRKKLRDA----GVIDIGYELTASKAIENIEETMKKYSKDWRNVDE 469

  Fly   417 -FNKINDDVD-----------NKEIAALTKNFSGAELEGLVRAAQSSAMNRLIKADAKVTVDPEA 469
             .||.:|.:.           ::|:..|...:...|.| |:|.|.:...:...|| .||....:.
  Fly   470 YLNKNHDPIKEWVTEEQLAKIHQEVRGLVDEYMRVEYE-LLREALAKDNDEKYKA-LKVKYPKKK 532

  Fly   470 MEKLK-----VNRDDFLHSLEHDIKPAFGTAQEI----LDNMLA------------RGVINWG-- 511
            .||.|     :..|..|.||.:::|.| |..:||    .|..:.            .|:...|
  Fly   533 KEKRKKKPKDMTGDRTLESLYNELKDA-GIIEEIGHRDFDEFITDFNFVADDTRDEDGLTTLGPA 596

  Fly   512 -APVSNLLEDGMLYVQQAKAPESSGLVSVLVAGAPNSGKTALAAQLAKMSDFPFVKVCSPEDMVG 575
             ..:..::::.||.:.:...|:..   |:|:.|..||||..|...:|...|..|:.: |||:...
  Fly   597 KGDIKMVIQESMLGMGEFDVPKPK---SLLLIGPLNSGKRLLCEIIASELDAVFMNL-SPENTYK 657

  Fly   576 YTESAK-----CLHIRKIF-------DDAYRSMLSCIVVDNVERLLDYGSIGPRYSNMTLQALLV 628
            |.:..|     .|.:.|.|       ::|:|.....:..:.||       |.||....:|.:.::
  Fly   658 YAKDLKYFLHVILKVAKAFQPTIMYIEEAHRLFWKKVPPEAVE-------INPRLLGTSLASKIL 715

  Fly   629 LLKKQPPKGRKLLILCTSSRREVLEEMEMLTAFTSVLHVPNLSKPDHVLAVLE 681
                :|.|....::|..:|.........:..||..||.:|........|..||
  Fly   716 ----KPLKKNDKIVLVGTSNMPWAANGGIKRAFQKVLLIPKCDYGTSFLLWLE 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011	7/26 (27%)
		SpoVK	242..699	CDD:223540	102/518 (20%)
		AAA	256..397	CDD:278434	27/166 (16%)
		AAA	539..668	CDD:278434	34/140 (24%)
CG14183	NP_649172.3	AAA	622..751	CDD:278434	34/140 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900