Protein Alignment comt and smid

DIOPT Version :9

• Sequence 1: NP_001259506.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 161/579 - (27%)
• Similarity: 247/579 - (42%)
• Gaps: 151/579 - (26%)

  Fly     4 ILKATKCPTDELSLTNRAIVNVGDFPEE----------------IKYADISPAPGQHFIFALEKT 52
            ::.||..|    .:.:..:..:|.|..|                |:...:|..|..::    :|.
  Fly   392 VIAATTRP----DVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLNY----DKI 448

  Fly    53 VEVPSGYVG---FSLVQRKWAMVSINQELEVRPYR--FDASSDVITCVSFETD------------ 100
            .|:..||||   .:||.|. |.|::.:. .::.:|  ..||...:|.|:.:.|
  Fly   449 AELTPGYVGADLMALVSRA-ASVAVKRR-SMKKFRELHAASEKNMTTVTLDDDEPSEDAGETPVP 511

  Fly   101 -----FLQKKTVSQEPYDSDQ--MAKEFIMQFAGMALTVGQSLVFNFKDKKLLG-LAVKSLEAID 157
                 ...|...:::..|.|:  .||:         .:.|.|.......|...| .::||.:...
  Fly   512 DSKGEETAKDAEAEQKVDGDKETSAKD---------KSEGDSPNIETPKKATNGNSSIKSPQKTP 567

  Fly   158 PKSLGEGKDTAM--RNV----------------------------RFGRILGN------------ 180
            .||..:..|.||  .||                            .....|.|
  Fly   568 KKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCL 632

  Fly   181 TVVQFEKAENSSLNLQGKSKGKVVRQSIIN-PD--WDFGKMGIGGLDKEFNSIFRRAFASRVFPP 242
            |::.|..|...   :|..:|    |:..|. ||  ||    .||.|:| .....:.|..:.|..|
  Fly   633 TLIDFVDAIKV---MQPSAK----REGFITVPDTTWD----DIGALEK-IREELKLAVLAPVKYP 685

  Fly   243 ELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKI----VNGPQILDKYVGESEANVR 303
            |::|:||.....|:||.||||.||||:|:.|     |.|..|    |.||::::.||||||..||
  Fly   686 EMLERLGLTAPSGVLLCGPPGCGKTLLAKAI-----ANEAGINFISVKGPELMNMYVGESERAVR 745

  Fly   304 RLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQR--GSVAGNSGVHDTVVNQLLTKIDGVDQLNN 366
            ..|..|.        ||...:|.|||.|::|.:|  |....|||..  :||||||::|||::...
  Fly   746 ACFQRAR--------NSAPCVIFFDEFDSLCPKRSDGGDGNNSGTR--IVNQLLTEMDGVEERKG 800

  Fly   367 ILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIAA 431
            :.::..|||.|:||.|:||||||:..:.:..|.:..|.:||...||..:. ..:.||||..||||
  Fly   801 VYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKR-PVLADDVDLDEIAA 864

  Fly   432 LTKNFSGAELEGLVRAAQSSAMNRLIKADAKVTVD---------PEAMEKLK--VNRDD 479
            .|:.::||:|.|||:.|...::.:.:. :....:|         .||:::|:  ||..|
  Fly   865 QTEGYTGADLAGLVKQASMFSLRQSLN-NGDTNLDDLCVRSQHFQEALQQLRPSVNEQD 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012	20/96 (21%)
		CDC48_2	111..>158	CDD:215011	10/49 (20%)
		SpoVK	242..699	CDD:223540	98/255 (38%)
		AAA	256..397	CDD:278434	63/146 (43%)
		AAA	539..668	CDD:278434
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	158/574 (28%)
		AAA	287..418	CDD:278434	6/29 (21%)
		P-loop_NTPase	679..>716	CDD:304359	18/36 (50%)
		AAA	699..830	CDD:278434	63/145 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810