DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment comt and CG5776

DIOPT Version :9

Sequence 1:	NP_001259506.1	Gene:	comt / 47091	FlyBaseID:	FBgn0000346	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001260420.1	Gene:	CG5776 / 34680	FlyBaseID:	FBgn0032450	Length:	799	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	107/312 - (34%)
Similarity:	171/312 - (54%)	Gaps:	52/312 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 KGKVVRQSII---NPDWDFGKMGIGGLDKEFNSIFRRAFASRVFPPELVEQLGCKHVKGILLYGP 261
            |...:|:.:|   |..|.    .||| ..|.....::|....:...:..::||.|..:|||::||
  Fly   518 KPSAMREVLIECPNVQWS----DIGG-QSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGP 577

  Fly   262 PGTGKTLMARQIGTMLNAREPKI----VNGPQILDKYVGESEANVRRLFAEAEEEEKRLGPNSGL 322
            ||..||::|:.:.|     |.|:    :.||::...:|||||..||.:|.:|    :::.|
  Fly   578 PGCSKTMIAKALAT-----ESKLNFLSIKGPELFSMWVGESERAVREVFRKA----RQVAP---- 629

  Fly   323 HIIIFDEIDAICKQR----GSVAGNSGVHDTVVNQLLTKIDGVDQLNNILVIGMTNRRDMIDEAL 383
            .|:.|||||||..:|    ||.:|:| |.:.|:.||||::|||:.|.|:.::..|||.||||:||
  Fly   630 AIVFFDEIDAIGGERSEGDGSSSGSS-VKERVLTQLLTELDGVEALQNVTIVAATNRPDMIDKAL 693

  Fly   384 LRPGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIAALTKNFSGAELEGLVRAA 448
            |||||::..:.:.||..:.|.:||.|..:.|    .|::|||.:::..||:.:||||::.:...|
  Fly   694 LRPGRIDRILYVGLPQCEARREILKIKLRAM----PISNDVDMEKLVQLTEGYSGAEIQAVCHEA 754

  Fly   449 QSSAMNRLIKA-DAKVTVDPEAMEKLKVNRDDFLHSLEHDIKPAFGTAQEIL 499
            ...|:.:..:| |.|.|              ||.|:|: .:.|.  |:.|:|
  Fly   755 ALRALEQSFEAEDVKWT--------------DFEHALK-AVPPR--TSPELL 789

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011
		SpoVK	242..699	CDD:223540	97/267 (36%)
		AAA	256..397	CDD:278434	62/148 (42%)
		AAA	539..668	CDD:278434
CG5776	NP_001260420.1	SpoVK	288..785	CDD:223540	104/306 (34%)
		AAA	307..447	CDD:278434
		AAA	572..707	CDD:278434	62/148 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810