Protein Alignment comt and Fign

DIOPT Version :10

• Sequence 1: NP_524877.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001099954.1
• Gene: Fign / 295649
• RGDID: 1308174
• Length: 759
• Species: Rattus norvegicus
• Alignment Length: 293
• Identity: 80/293 - (27%)
• Similarity: 128/293 - (43%)
• Gaps: 57/293 - (19%)

  Fly   186 EKAENSSLNLQGKSKGKVVRQSIINP--DWDFGKMGIGGLDKEFNSIFRRAFASRVFPPELVEQL 248
            |:.:|:..:|......:::.|   .|  ||.    .|.|||     :.:......|..|.|....
  Rat   459 EQLKNTDTHLIDLVTNEIITQ---GPPVDWS----DIAGLD-----LVKAVIKEEVLWPVLRSDA 511

  Fly   249 --GCKHV-KGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANVRRLFAEAE 310
              |...: :.|||:||.||||||:.|.|.:.|.|...||. |..::.|::||:|..:...|..|.
  Rat   512 FSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIA-GSGLVAKWLGEAEKIIHASFLVAR 575

  Fly   311 EEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVV---NQLLTKIDGV-----DQLNNI 367
            ..:    |:    :|...:||.:...:.|..     |..|.   .:.|.::|.|     ||   |
  Rat   576 CRQ----PS----VIFVSDIDMLLSSQVSEE-----HSPVSRMRTEFLMQLDTVLTSAEDQ---I 624

  Fly   368 LVIGMTNRRDMIDEALLR--PGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIA 430
            :||..|::.:.|||:|.|  ..||.:.:..|....|..||:|:.|          |..:::||.|
  Rat   625 VVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQH----------NYCLNDKEFA 679

  Fly   431 AL---TKNFSGAELEGLVRAAQSSAMNRLIKAD 460
            .|   |:.|||.::..|.:.|....::.:...|
  Rat   680 LLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATD 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_524877.1	CDC48_N	5..83	CDD:215012
		CDC48_2	111..>158	CDD:215011
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	55/188 (29%)
		CDC48	<220..>606	CDD:273521	73/257 (28%)
		SpoVK	<526..702	CDD:440232
Fign	NP_001099954.1	RecA-like_fidgetin	487..650	CDD:410931	55/184 (30%)
		AAA_lid_3	675..>706	CDD:465537	10/30 (33%)
		Vps4_C	<723..756	CDD:462762