Protein Alignment comt and ZK938.3

DIOPT Version :9

• Sequence 1: NP_001259506.1
• Gene: comt / 47091
• FlyBaseID: FBgn0000346
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001364588.1
• Gene: ZK938.3 / 191468
• WormBaseID: WBGene00014160
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 110/561 - (19%)
• Similarity: 187/561 - (33%)
• Gaps: 220/561 - (39%)

  Fly    46 IFALEKTVEVPSG----YVGFSLVQR------KWAMVS------INQELEVRPYRFDASSDVITC 94
            :|....|..:.||    |:..|..|.      .|.|:|      ....|||:.          .|
 Worm   121 VFTKIPTTHIESGFDEFYISHSFTQEDVAITSTWRMISQAAIGHHEHHLEVKR----------AC 175

  Fly    95 ---VSFETDFLQKKT---VSQEPYDSDQMAKEFIMQFAGMALTVGQSLVFNFKDKKLLGLAVKSL 153
               .:|...||:.:|   :..|..:::|..:...:::|.:.:            :||    .:..
 Worm   176 QEQKAFRESFLKTQTDFDIDFENAEAEQETQLLSIEYAVLII------------QKL----ERKY 224

  Fly   154 EAIDPKSLGEGKDTAMRN-VRFGR----ILGNTVVQFEKAENSSLNLQGKSKG----KVVRQ--- 206
            :||           :.|| |||.|    .|....|:.: |..:::.:|.:::|    |:||:
 Worm   225 QAI-----------SRRNYVRFVRERAAELHGLKVEID-ATQAAIRIQARTRGYFARKLVREMRE 277

  Fly   207 ---SIIN--PDWDFGKM--------------GIGGLD-----KEFN------------------- 228
               :|:|  |:....|.              |:||.:     :|||
 Worm   278 KELNILNMTPESYIRKRCAERERKRKEGLAGGVGGGEIIEQIEEFNTDLAEALKLLKTHFFFPTS 342

  Fly   229 ------------------SIFRRAFASRVFPP-------ELVEQ--------------------- 247
                              :|||.|....:..|       ||..|
 Worm   343 DLTDIKPSALPIDLNNQETIFRDACFRGIVSPLAQIELSELTSQREICKIENRQFKFDFRSFLVQ 407

  Fly   248 -------LGC--------KHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGE 297
                   ||.        :.::.:||.|.|.:|||..||.|....:      |....|....|..
 Worm   408 TVCTPCSLGTWQKQKSKDQKMQWLLLSGAPDSGKTTWARAISRACH------VTHVHISKNVVNM 466

  Fly   298 SEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLLTKIDGVD 362
            .:..:..:..:..::||||       ::..|.||.:.|        ...|....::.:...:.:.
 Worm   467 GKRKIYTVVKKLAKQEKRL-------LVSIDRIDVMKK--------DPKHKGYTHRQILLRNFLS 516

  Fly   363 QLNNI---LVIGMTN-RRDMIDEAL--LRPGRLEVQMEISLPNEQGRVQIL------NIHTKRMR 415
            .|:||   :|||||. ..|.:|..:  |.|    :|..:|.|....|..:.      |...:|:.
 Worm   517 DLSNIKFVMVIGMTRVPLDDLDSYISDLFP----LQATLSNPTNATRYDLAVDCLSRNWEQERLP 577

  Fly   416 EF-NKINDDVDNKEIAALTKNFSGAELEGLVRAAQSSAMNR 455
            :| |:|.|      |...||:.:..:....|....|:|.|:
 Worm   578 KFPNRIFD------IEKQTKDQTRGKAAKFVTNRWSAANNK 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
comt	NP_001259506.1	CDC48_N	5..83	CDD:215012	13/52 (25%)
		CDC48_2	111..>158	CDD:215011	6/46 (13%)
		SpoVK	242..699	CDD:223540	57/270 (21%)
		AAA	256..397	CDD:278434	35/146 (24%)
		AAA	539..668	CDD:278434
ZK938.3	NP_001364588.1	P-loop_NTPase	431..545	CDD:422963	32/134 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900