DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adf1 and CG4404

DIOPT Version :9

Sequence 1:	NP_001260730.1	Gene:	Adf1 / 47082	FlyBaseID:	FBgn0284249	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_572838.2	Gene:	CG4404 / 32241	FlyBaseID:	FBgn0030432	Length:	308	Species:	Drosophila melanogaster

Alignment Length:	244	Identity:	57/244 - (23%)
Similarity:	97/244 - (39%)	Gaps:	73/244 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FDLNLIEAVKLNPVIYDRSH--YNYKHFVRKAQTWKQIAETLGVPEQKCTKRWKSLRDKFAREMK 74
            |::..::.|:..|.:::.:|  |:.|..|::|  |:|:|..:....:.|.:||:::|..|.|.:|
  Fly    14 FNVRFVQFVENQPCLWNYTHPGYSKKEDVQRA--WQQVANDIKDTVRNCRERWRTIRSSFLRSLK 76

  Fly    75 LCQ----ESRWRYF--KQMQFLV--DSIRQYRESLLGKCANGSQSANQVADPSQQQQAQQQTVVD 131
            |.:    ..:.:|:  |.:||||  ...|...:.|.|..         :..|.|...|||:..|
  Fly    77 LARTQTGRGKRKYYLSKYLQFLVPFTKSRSCHKQLPGMV---------LRKPGQAATAQQEDEV- 131

  Fly   132 IFAQPFNGSATTSAQALTHPHEITVTSDAQLATAVGKDQKPYFYEPPLKRERSEEEHSDNM---- 192
                                    |.::.:...:.|        |.||..:.|||||..|.
  Fly   132 ------------------------VAAEEEAKVSDG--------EMPLDVQVSEEEHRRNQEQDR 164

  Fly   193 ----------LNTIKI--FQNNVSQAVS--AEDQSFGMVVTDML-NTLG 226
                      |::||:  ..:|.:|.:.  ...||...|....| |.||
  Fly   165 EQPTACLPLRLHSIKVEHDSSNANQQLERMVSQQSLVSVPAAALGNHLG 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adf1	NP_001260730.1	MADF	15..95	CDD:214738	24/89 (27%)
CG4404	NP_572838.2	MADF	17..103	CDD:214738	24/87 (28%)
CG4404	NP_572838.2	BESS	267..301	CDD:281011
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438507
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840