DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acj6 and Pou5f2

DIOPT Version :9

Sequence 1:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_083591.1	Gene:	Pou5f2 / 75507	MGIID:	1922757	Length:	329	Species:	Mus musculus

Alignment Length:	163	Identity:	63/163 - (38%)
Similarity:	92/163 - (56%)	Gaps:	22/163 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 LHPDTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGA-----LSQSTICRFESLT 278
            |..|.....:|:|..|:..:|:|:.||.:|||||.|        |||     |||:||||||:..
Mouse   104 LPEDVSAIQKEMEQLAKELRQKRMTLGYSQADVGFA--------VGAMFGKVLSQTTICRFEAQQ 160

  Fly   279 LSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKR---SLEAYFA 340
            ||..||..|:|:|:.||||.:  .||.........:|....|:|:    |:.|:|   :||..|.
Mouse   161 LSLANMWKLRPLLKMWLEEVD--EKNLLGICRMEMILEQARKRRR----ASRERRIGSNLEKLFL 219

  Fly   341 VQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQ 373
            ..|.|:.::|:.||.:|.|:|::|:|||.|:.|
Mouse   220 QCPEPTPQQISYIAGRLRLQKDLVQVWFSNRSQ 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	37/81 (46%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	20/54 (37%)
Pou5f2	NP_083591.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Pou	113..181	CDD:278582	36/75 (48%)
		Homeobox	<214..250	CDD:278475	15/35 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847031
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740