DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acj6 and Pou5f2

DIOPT Version :9

Sequence 1:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001075220.2	Gene:	Pou5f2 / 680620	RGDID:	1589456	Length:	335	Species:	Rattus norvegicus

Alignment Length:	163	Identity:	63/163 - (38%)
Similarity:	92/163 - (56%)	Gaps:	22/163 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 LHPDTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGA-----LSQSTICRFESLT 278
            |..|.....:|:|..|:..:|:|:.||.:|||||.|        |||     |||:||||||:..
  Rat   110 LPEDVSAIQKEMEQLAKELRQKRMTLGYSQADVGFA--------VGAMFGKVLSQTTICRFEAQQ 166

  Fly   279 LSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKR---SLEAYFA 340
            ||..||..|:|:|:.||||.:  .||.........:|....|:|:    |:.|:|   :||..|.
  Rat   167 LSLANMWKLRPLLKMWLEEVD--EKNLLGICRMEMILQQARKRRR----ASRERRIGSNLEKLFL 225

  Fly   341 VQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQ 373
            ..|.|:.::|:.||.:|.|:|::|:|||.|:.|
  Rat   226 QCPEPTPQQISYIAGRLRLQKDLVQVWFSNRSQ 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	37/81 (46%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	20/54 (37%)
Pou5f2	NP_001075220.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Pou	119..187	CDD:395105	36/75 (48%)
		homeodomain	<220..256	CDD:412151	15/35 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350537
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840