Protein Alignment acj6 and POU4F1

DIOPT Version :10

• Sequence 1: NP_524876.1
• Gene: acj6 / 47080
• FlyBaseID: FBgn0000028
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_006228.3
• Gene: POU4F1 / 5457
• HGNCID: 9218
• Length: 419
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 203/461 - (44%)
• Similarity: 240/461 - (52%)
• Gaps: 124/461 - (26%)

  Fly     3 MSMYSTTDKMKMSAPSCFPGRYSPSYRSSEQMRR-CMPNPSIHISSSCDSLESRLLEDASLLCNS 66
            |||.|......|. |:....:|...:.|||.:|| |:|.|.:
Human     2 MSMNSKQPHFAMH-PTLPEHKYPSLHSSSEAIRRACLPTPPL----------------------- 42

  Fly    67 WSARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHVHSQMPSQIKHDVMYHHHSMSGPPQRPLQ 131
                 ..::||.:::.:|:||||||||||...|.:      ....|.|..|  |:|:..|.....
Human    43 -----QSNLFASLDETLLARAEALAAVDIAVSQGK------SHPFKPDATY--HTMNSVPCTSTS 94

  Fly   132 ENPFSRQMHH-----SMDQLDMLDPTGSMTTLAPIS---------------ESP----------- 165
            ..|.:...||     :::..|:||...| .:||.::               :.|
Human    95 TVPLAHHHHHHHHHQALEPGDLLDHISS-PSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGG 158

  Fly   166 -----------------------LTPTHQHLHGSYHSMNHMMSH-------------HHPGTLSG 194
                                   |.....|.|...||:.| :||             .|||.::
Human   159 PGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGH-LSHPAAAAAMNMPSGLPHPGLVA- 221

  Fly   195 HTGGHHGHSA----------VHHPVITAAVAAAGLHP--DTDTDPRELEAFAERFKQRRIKLGVT 247
             ...|||.:|          .......|.|.||||..  |:||||||||||||||||||||||||
Human   222 -AAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVT 285

  Fly   248 QADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAP 312
            |||||.||||||:||||:||||||||||||||||||||||||||||||||||...:.|...|:
Human   286 QADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPE-- 348

  Fly   313 SVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 377
             :...|||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||
Human   349 -LFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 412

  Fly   378 IVSSVT 383
            :..|.|
Human   413 MKFSAT 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	72/76 (95%)
		Homeodomain	321..377	CDD:459649	54/55 (98%)
POU4F1	NP_006228.3	POU-IV box	57..66		8/8 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..117		4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..197		6/65 (9%)
		POU	260..337	CDD:197673	72/76 (95%)
		Homeodomain	356..412	CDD:459649	54/55 (98%)