Protein Alignment acj6 and CCHCR1

DIOPT Version :10

• Sequence 1: NP_524876.1
• Gene: acj6 / 47080
• FlyBaseID: FBgn0000028
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_001381570.1
• Gene: CCHCR1 / 54535
• HGNCID: 13930
• Length: 880
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 85/487 - (17%)
• Similarity: 161/487 - (33%)
• Gaps: 168/487 - (34%)

  Fly     4 SMYSTTDKMKMSAPSCFPGRYSPSYRSSEQMRRCMPNPSIHISSSCDSLESRLLEDASLLCNSWS 68
            |:::|.:.:::...|.   .:..:.:..|..|:..|:         ||||.........|.|.|
Human   384 SLHATAELLQVRVQSL---THILALQEEELTRKVQPS---------DSLEPEFTRKCQSLLNRW- 435

  Fly    69 ARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHVHSQMPSQIKHDVMYHHHSMSGPP------Q 127
                              .|.:.|:.:|....:..||....|:|..|......::...      |
Human   436 ------------------REKVFALMVQLKAQELEHSDSVKQLKGQVASLQEKVTSQSQEQAILQ 482

  Fly   128 RPLQENP--------------------------FSRQMHHSMDQLDMLDPTGSM------TTLAP 160
            |.||:..                          :.:|...:.:||.::....|.      ||:|.
Human   483 RSLQDKAAEVEVERMGAKGLQLELSRAQEARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAK 547

  Fly   161 ISESPLTPTHQHLHGSYHSMNHMMSH-----HHPGTLSGHTGGHHGHSAVHHPVITAAVAAAGLH 220
            :..:.         ....|:|:.:|:     |   |:.|              :|...:|.|.|.
Human   548 VEGAA---------AQLPSLNNRLSYAVRKVH---TIRG--------------LIARKLALAQLR 586

  Fly   221 --------PDTDTDPRELEAFAERFKQRRIKLGVT----QADVGKA------------------- 254
                    |.||.. .||:...|...:...:|.::    |.:||:|
Human   587 QESCPLPPPVTDVS-LELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLE 650

  Fly   255 ---------LANLKL------PGVGALSQSTICRFESLTLS--------HNNMIALKPILQAWLE 296
                     ||:|.|      .|....::......:.||..        ...:..::..|:..|.
Human   651 QELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEKVAEVETRLREQLS 715

  Fly   297 EAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQP---RPSGEKIAAIAEKLD 358
            :.|.:....||: .|.:|:...:.:|:    ||.||...:....:|.   :..|:::|...::|:
Human   716 DTERRLNEARRE-HAKAVVSLRQIQRR----AAQEKERSQELRRLQEEARKEEGQRLARRLQELE 775

  Fly   359 LKKNVVRVWFCNQ----RQKQKRIVSSVTPSM 386
            ..||::......:    |.||:|:: :|.||:
Human   776 RDKNLMLATLQQEGLLSRYKQQRLL-TVLPSL 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	19/122 (16%)
		Homeodomain	321..377	CDD:459649	14/62 (23%)
CCHCR1	NP_001381570.1	HCR	125..871	CDD:284517	85/487 (17%)