Protein Alignment acj6 and POU2F1

DIOPT Version :10

• Sequence 1: NP_524876.1
• Gene: acj6 / 47080
• FlyBaseID: FBgn0000028
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: XP_011507955.1
• Gene: POU2F1 / 5451
• HGNCID: 9212
• Length: 769
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 114/369 - (30%)
• Similarity: 166/369 - (44%)
• Gaps: 96/369 - (26%)

  Fly    83 ILSRAEA---LAAVDIQKHQAQHVHSQMPSQIKHDVMYHHHSMSGPPQRPLQENPFS-------- 136
            :|.:|:|   |.|..:|:|.|...||...:.|           |.....|:.:.|.|
Human   148 LLQQAQAQAQLLAAAVQQHSASQQHSAAGATI-----------SASAATPMTQIPLSQPIQIAQD 201

  Fly   137 -------RQMHHSMDQLDMLDPTGSMTTLAP----ISESP------------LTPTHQHLHGSYH 178
                   :|.:.::.|..::.||   |.|.|    ||::|            ||...|      .
Human   202 LQQLQQLQQQNLNLQQFVLVHPT---TNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQ------Q 257

  Fly   179 SMNHMMSHHHPGTLSGHTGGHHGHSAVHHPVITAAVAAAGLHPDTDTDPR--------------E 229
            |..:::......||:         |....|..|.|.......|.:.:.|:              |
Human   258 SQANLLQSQPSITLT---------SQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEE 313

  Fly   230 LEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAW 294
            ||.||:.|||||||||.||.|||.|:.  ||.| ...||:||.|||:|.||..||..|||:|:.|
Human   314 LEQFAKTFKQRRIKLGFTQGDVGLAMG--KLYG-NDFSQTTISRFEALNLSFKNMCKLKPLLEKW 375

  Fly   295 LEEAE-AQAKNKRRDPDA---PSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAE 355
            |.:|| ..:.:....|.|   |.:.....:::|||||....:.:||..|....:|:.|:|..||:
Human   376 LNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIAD 440

  Fly   356 KLDLKKNVVRVWFCNQRQKQKRI------------VSSVTPSMT 387
            :|:::|.|:||||||:|||:|||            :.::.||.|
Human   441 QLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPT 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	42/90 (47%)
		Homeodomain	321..377	CDD:459649	25/55 (45%)
POU2F1	XP_011507955.1	POU	306..380	CDD:197673	41/76 (54%)
		Homeodomain	406..462	CDD:459649	25/55 (45%)
		POU2F1_C	476..755	CDD:437368	3/9 (33%)