DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acj6 and Pou3f3

DIOPT Version :9

Sequence 1:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_032926.2	Gene:	Pou3f3 / 18993	MGIID:	102564	Length:	497	Species:	Mus musculus

Alignment Length:	303	Identity:	115/303 - (37%)
Similarity:	154/303 - (50%)	Gaps:	51/303 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 HHHSMSGPPQRPLQENPFSRQMHHSMDQLDMLDP----------TGSMTTLAP---ISESPLTPT 169
            |..||:|..|.|.|...:|:....:::.:....|          .|:.:.:.|   ..::|....
Mouse   204 HLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAE 268

  Fly   170 HQHLHGSYHSMNHMMSHHHPGTLSGHTGGHHGHSAVHHPVITAAVAAAGL-----HPDTDTDPR- 228
            |.|.|       |..:|.||    .|.  ||.....||   ....|..||     |.|.||...
Mouse   269 HHHHH-------HHHAHPHP----PHP--HHAQGPPHH---GGGGAGPGLNSHDPHSDEDTPTSD 317

  Fly   229 ELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQA 293
            :||.||::|||||||||.||||||.||..|.   ....||:||||||:|.||..||..|||:|..
Mouse   318 DLEQFAKQFKQRRIKLGFTQADVGLALGTLY---GNVFSQTTICRFEALQLSFKNMCKLKPLLNK 379

  Fly   294 WLEEAEAQAKNKRRDPDAPSVLPA-GEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKL 357
            |||||::...:    |.:...:.| |.|::|||||....|.:||::|...|:||.::|..:|:.|
Mouse   380 WLEEADSSTGS----PTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSL 440

  Fly   358 DLKKNVVRVWFCNQRQKQKRI----VSSVTP----SMTGHGSA 392
            .|:|.||||||||:|||:||:    :...||    |..|..||
Mouse   441 QLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSA 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	46/77 (60%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	28/53 (53%)
Pou3f3	NP_032926.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..62
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	121..189
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..316		23/101 (23%)
		POU	311..385	CDD:197673	45/76 (59%)
		Homeobox	406..460	CDD:395001	28/53 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	458..497		8/26 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847030
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740