DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acj6 and Pou3f1

DIOPT Version :9

Sequence 1:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_035271.1	Gene:	Pou3f1 / 18991	MGIID:	101896	Length:	449	Species:	Mus musculus

Alignment Length:	259	Identity:	104/259 - (40%)
Similarity:	139/259 - (53%)	Gaps:	41/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 MHHSMDQLDMLDPTGSMTTLAPISESPLTPTHQHLHGSYHSMNHMMSHHHPGTLSGHTGGHHGHS 203
            :||::.:      .|....|.|   ||  |.|...||  |:..|           .|.||.|..:
Mouse   185 LHHALHE------DGHEAQLEP---SP--PPHLGAHG--HAHGH-----------AHAGGLHAAA 225

  Fly   204 AVHHPVITAAVAAAGLHPDTDT-DPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALS 267
            |..||......::.|.|.|.|. ...:||.||::|||||||||.||||||.||..|.   ....|
Mouse   226 AHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLY---GNVFS 287

  Fly   268 QSTICRFESLTLSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEK 332
            |:||||||:|.||..||..|||:|..||||.::.:.:   ..:...:...|.|::|||||....|
Mouse   288 QTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGS---PTNLDKIAAQGRKRKKRTSIEVGVK 349

  Fly   333 RSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRIVSSVTPSMTGHGSAGFGY 396
            .:||::|...|:||..:|..:|:.|.|:|.||||||||:|||:||    :||      :||.|:
Mouse   350 GALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKR----MTP------AAGAGH 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	45/77 (58%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	28/53 (53%)
Pou3f1	NP_035271.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	76..108
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	132..152
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	184..251		24/89 (27%)
		POU	245..319	CDD:197673	44/76 (58%)
		Homeobox	340..393	CDD:278475	28/52 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	393..449		7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847020
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740