DRSC/TRiP Functional Genomics Resources

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Protein Alignment acj6 and POU5F2

DIOPT Version :10

Sequence 1:NP_524876.1 Gene:acj6 / 47080 FlyBaseID:FBgn0000028 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_694948.1 Gene:POU5F2 / 134187 HGNCID:26367 Length:328 Species:Homo sapiens


Alignment Length:165 Identity:65/165 - (39%)
Similarity:95/165 - (57%) Gaps:22/165 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   228 RELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGA-----LSQSTICRFESLTLSHNNMIAL 287
            :||:..|:..:|:|:.||.:|||||.|        |||     |||:||||||:..||..||..|
Human   124 KELQQLAKELRQKRLSLGYSQADVGIA--------VGALFGKVLSQTTICRFEAQQLSVANMWKL 180

  Fly   288 KPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKR---SLEAYFAVQPRPSGEK 349
            :|:|:.||:|.||:  |.........:|....|.|:    |:.|:|   |||.:|...|:|:.::
Human   181 RPLLKKWLKEVEAE--NLLGLCKMEMILQQSGKWRR----ASRERRIGNSLEKFFQRCPKPTPQQ 239

  Fly   350 IAAIAEKLDLKKNVVRVWFCNQRQKQKRIVSSVTP 384
            |:.||..|.|:|:||||||.|:.:...|..:..:|
Human   240 ISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASP 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
acj6NP_524876.1 POU 222..299 CDD:197673 35/75 (47%)
Homeodomain 321..377 CDD:459649 23/58 (40%)
POU5F2NP_694948.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
Pou 121..192 CDD:459692 35/75 (47%)
Homeodomain <225..261 CDD:459649 17/35 (49%)
Blue background indicates that the domain is not in the aligned region.

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