DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acj6 and pou4f2

DIOPT Version :9

Sequence 1:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_002938977.2	Gene:	pou4f2 / 100498428	XenbaseID:	XB-GENE-854899	Length:	379	Species:	Xenopus tropicalis

Alignment Length:	406	Identity:	198/406 - (48%)
Similarity:	236/406 - (58%)	Gaps:	90/406 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SMYSTTDKMKMSAPSCFPGRYSPSY--------RSSEQMRR-CMPNPSIHISSSCDSLESRLLED 59
            :::|::.....||.|      |||.        .|||.||| |:|.|.
Frog    27 ALHSSSPHSSSSATS------SPSISRAGGGNGSSSEAMRRACLPTPP----------------- 68

  Fly    60 ASLLCNSWSARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHVHSQMPSQIKHDVMYHHHSMSG 124
                         .:||.|:::.:|:||||||||||.        ||..||..|   :|||:...
Frog    69 -------------SNIFGGLDESLLARAEALAAVDIV--------SQCKSQHHH---HHHHTPHH 109

  Fly   125 PPQRPLQENPFSRQMHHSMDQLDMLDPTGSMTTLAPISE-SPLTPTHQHLHGSYHSM---NHMMS 185
            .|.:|       ...:|:|:.:..  .:.|.::..|||. |.:..:|.|.|..:|..   ..::.
Frog   110 SPFKP-------DATYHTMNTIPC--TSASSSSSVPISHPSGVAGSHHHHHHHHHHQPLEGELLD 165

  Fly   186 HHHPG-TLSGHTGGH--------HGHSAVHHPVITAAVAAAGLH---------PDTDTDPRELEA 232
            |..|| ||...||..        |.|.|..:|:..||::.|..|         .|.|.|||:|||
Frog   166 HITPGLTLGAITGPDGSVVSTPGHPHMASMNPMHQAALSMAHAHGLPTHMGCMSDVDADPRDLEA 230

  Fly   233 FAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEE 297
            ||||||||||||||||||||.||||||:||||:||||||||||||||||||||||||||||||||
Frog   231 FAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEE 295

  Fly   298 AEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKN 362
            ||   |:.|.....|.:....||||||||||||||||||||||:|||||.|||||||||||||||
Frog   296 AE---KSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKN 357

  Fly   363 VVRVWFCNQRQKQKRI 378
            |||||||||||||||:
Frog   358 VVRVWFCNQRQKQKRM 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	70/76 (92%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	51/53 (96%)
pou4f2	XP_002938977.2	POU	220..297	CDD:197673	70/76 (92%)
pou4f2	XP_002938977.2	Homeobox	318..372	CDD:395001	51/53 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	141	1.000	Domainoid score	I4673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2611
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D396215at33208
OrthoFinder	1	1.000	-	-		FOG0001337
OrthoInspector	1	1.000	-	-		otm49366
Panther	1	1.100	-	-	O	PTHR11636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X830
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070