DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acj6 and pou4f1

DIOPT Version :9

Sequence 1:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_002931972.1	Gene:	pou4f1 / 100488759	XenbaseID:	XB-GENE-853139	Length:	371	Species:	Xenopus tropicalis

Alignment Length:	415	Identity:	202/415 - (48%)
Similarity:	240/415 - (57%)	Gaps:	80/415 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MSMYSTTDKMKMSAPSCFPGRYSPSYRSSEQMRR-CMPNPSIHISSSCDSLESRLLEDASLLCNS 66
            |||.|......|. ||....:|:..:.|||.:|| |:|.|.:
Frog     2 MSMNSKQPHFAMH-PSLPEHKYTSLHSSSEAIRRACLPTPPM----------------------- 42

  Fly    67 WSARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHVHSQMPSQIKHDVMYHH------HSMSGP 125
                 ..:|||.:::.:|:||||||||||...|.:. |...|     |..||.      .:.|..
Frog    43 -----QSNIFASLDETLLARAEALAAVDIAVSQGKS-HPYKP-----DATYHTMNSVQCSNNSSV 96

  Fly   126 PQRPLQENPFSRQMHHSMDQLDMLD--PTGSMTTLAP------------------ISESPLTPTH 170
            |..|...:......|.:::..|:|:  .:.|:..:|.                  :..|| ...|
Frog    97 PLGPHHHHHHHHHHHQALEPGDLLEHVASPSLALMASTGHEGVGGGGGGGGGGGGLMSSP-GHHH 160

  Fly   171 QHLHGSYH-----SMNHMMSHHHPGTLSGHTGGHHGHSAVHHPVITAAVAAAGLHP--DTDTDPR 228
            .|:||..|     :||...:..|||.::    .|||...   .|.:|..|||||..  |::||||
Frog   161 SHMHGLSHLSHQAAMNMTSALQHPGLVA----AHHGPGG---QVASAVGAAAGLASICDSETDPR 218

  Fly   229 ELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQA 293
            ||||||||||||||||||||||||.||||||:||||:||||||||||||||||||||||||||||
Frog   219 ELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQA 283

  Fly   294 WLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLD 358
            ||||||...:.|...|:   :...|||||||||||||||||||||||||||||.|||||||||||
Frog   284 WLEEAEGAQREKLNKPE---LFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLD 345

  Fly   359 LKKNVVRVWFCNQRQKQKRIVSSVT 383
            |||||||||||||||||||:..|.|
Frog   346 LKKNVVRVWFCNQRQKQKRMKFSAT 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acj6	NP_524876.1	POU	222..299	CDD:197673	71/76 (93%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	52/53 (98%)
pou4f1	XP_002931972.1	POU	212..289	CDD:197673	71/76 (93%)
pou4f1	XP_002931972.1	Homeobox	310..364	CDD:365835	52/53 (98%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	141	1.000	Domainoid score	I4673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2611
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D396215at33208
OrthoFinder	1	1.000	-	-		FOG0001337
OrthoInspector	1	1.000	-	-		otm49366
Panther	1	1.100	-	-	LDO	PTHR11636
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2889
SonicParanoid	1	1.000	-	-		X830
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100