Protein Alignment NCK1 and cdc15

DIOPT Version :9

• Sequence 1: NP_001278928.1
• Gene: NCK1 / 4690
• HGNCID: 7664
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_593322.1
• Gene: cdc15 / 2541975
• PomBaseID: SPAC20G8.05c
• Length: 927
• Species: Schizosaccharomyces pombe
• Alignment Length: 255
• Identity: 52/255 - (20%)
• Similarity: 95/255 - (37%)
• Gaps: 68/255 - (26%)

Human    41 VRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVD----PG 101
            :|:|.:.....||..:.|::|..:.|..:: ..:|.:.:       .|..|||..:...    .|
pombe   690 LRHSRSNMSRSPSPMLSRRSSTLRPSFERS-ASSLSVRQ-------SDVVSPAPSTRARGQSVSG 746

Human   102 ERLYDLNMPAYVKFNYMAEREDELSL------------IKGTKVIVMEKCSDGWWRGSYNGQVGW 154
            ::....:|..|.::|   :.:.:||:            .:.:.|:..:|.:........||
pombe   747 QQRPSSSMSLYGEYN---KSQPQLSMQRSVSPNPLGPNRRSSSVLQSQKSTSSNTSNRNNG---- 804

Human   155 FPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQ----------------------------- 190
               .|......|.:|...||:|.:....|:..:|.:
pombe   805 ---GYSGSRPSSEMGHRYGSMSGRSMRQVSQRSTSRARSPEPTNRNSVQSKNVDPRATFTAEGEP 866

Human   191 VLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKI---NGMVGLVPKNYV 247
            :|..|.|||.:.:...||::|:|||.:.|:...|:.  ||....|   |...||.|.|:|
pombe   867 ILGYVIALYDYQAQIPEEISFQKGDTLMVLRTQEDG--WWDGEIINVPNSKRGLFPSNFV 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NCK1	NP_001278928.1	SH3_Nck1_1	3..61	CDD:212833	5/19 (26%)
		SH3_Nck1_2	108..162	CDD:212834	10/65 (15%)
		SH3_Nck1_3	193..249	CDD:212837	21/58 (36%)
		SH2_Nck1	280..376	CDD:198271
cdc15	NP_593322.1	F-BAR_PombeCdc15_like	28..263	CDD:153335
		SH3	869..925	CDD:214620	21/58 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	43	1.000	Domainoid score	I4102
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000